Chemistry of Natural Compounds

, Volume 54, Issue 5, pp 1015–1017 | Cite as

Constituents of the Aerial Parts of Centaurea behen

  • Mahmoud Mosaddegh
  • Majid Tavakoli
  • Sahar BehzadEmail author

The large genus Centaurea consists of more than 700 species [1], from which 75 species are found in Iran. They are widespread around the country. In Iran their common name is Gole-gandom. Centaurea behen (Gole-Gandome-Talaei in Persian) is a perennial plant 60–200 cm tall that is traditionally used as a tonic for jaundice, cystic fibrosis, and impotence. It is an Irano–Turanian plant grows on stony hillsides, meadows, and along the roadsides [2]. Several sesquiterpene lactones of the guaianolide type (cynaripicrin, arguerin B, deacylcynaropicrine, grosshemin, and 4β,15-dihydro-3-dehydrosolstitialin A) [3, 4], two methoxylated flavone (crisimaritin and jeceosidin) [4, 5], and a flavonoid aglycone (luteolin) [6] were isolated from the leaves of Centaurea behen. In this study, fractionation of the petroleum ether and chloroform extracts of Centaurea behen L. resulted in the isolation of two methoxylated flavones, two triterpenes, and sterols. All compounds were isolated from C. behenfor...



The authors are grateful to Dr. Seyed Mustafa Ghanadian (Isfahan Pharmaceutical Sciences Research Center, Isfahan, Iran) for his valuable assistance in providing NMR spectra.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Mahmoud Mosaddegh
    • 1
    • 2
  • Majid Tavakoli
    • 3
  • Sahar Behzad
    • 1
    • 4
    Email author
  1. 1.Department of Pharmacognosy, School of PharmacyShahid Beheshti University of Medical SciencesTehranIran
  2. 2.Traditional Medicine and Materia Medica Research CenterShahid Beheshti University of Medical SciencesTehranIran
  3. 3.Lorestan Agricultural and Natural Resourses Research CenterLorestanIran
  4. 4.Evidence-based Phytotherapy and Complementary Medicine Research CenterAlborz University of Medical SciencesKarajIran

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