Chemistry of Natural Compounds

, Volume 54, Issue 5, pp 1004–1008 | Cite as

Neuroprotective Sesquiterpenes from Capsella bursa-pastoris

  • Qinge MaEmail author
  • Rongrui WeiEmail author
  • Zhongling Cao

Capsella bursa-pastoris belongs to the Brassicaceae family and is consuned as a popular vegetable in folk recipes. C. bursa-pastoris is an annual or biennial herb that is widely distributed in most areas of China. Moreover, C. bursa-pastoris has always been used as a medicinal plant for treating metrorrhagia, conjunctivitis, vomiting, and hydropsy [1]. Previous phytochemical investigations of C. bursa-pastoris have displayed the presence of flavonoids [2], essential oils [3], amino acids [4], and alkaloids [5]. Modern pharmacology has revealed that C. bursa-pastoris has many biological activities, such as hepatoprotective [6], anti-oxidant [7], anti-tumor [8], anti-microbial [9], anti-hypertensive [10], and anti-inflammatory [11].

To the best of our knowledge, there have been no reports on the neuroprotective activities of C. bursa-pastoris, which prompted us to investigate further its pharmacological potentials. As a result, 12 compounds (112) were isolated and identified as...



This work was supported by the Key Scientific Research Project of Colleges and Universities in Henan Province (Based PC12 Cell-Studies on Neuroprotective Components of Magnolia biondii Pamp.).


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Authors and Affiliations

  1. 1.State Key Laboratory of Innovative Drugs and High Efficiency Energy Saving and Consumption Reduction Pharmaceutical Equipment, Key Laboratory of Modern Preparation of TCM of Ministry of Education, Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic MedicineJiangxi University of Traditional Chinese MedicineNanchangP. R. China
  2. 2.College of Chemistry and Pharmaceutical EngineeringNanyang Normal UniversityNanyangP. R. China

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