Resveratrol Oligomers from the Stem Bark of Vatica mangachapoi
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Vatica, a genus comprising about 65 species, belongs to the largest subfamily Dipterocarpoideae in the family Dipterocarpaceae, most of which are tall, hardy, and evergreen trees primarily distributed throughout Southeast Asia, especially in Indonesia and Malaysia , south and east India, and Sri Lanka. This genus is well documented to be a rich source of biologically active resveratrol oligomers. As a phytoestrogen, resveratrol and its oligomers have recently attracted attentions because of their multifunctional bioactivities that may account for its possible cardioprotective action, including smooth muscle cell proliferation and platelet aggregration , chemoprevention of cancers , activation of human SIRT1 , and anti HIV effect . Because of its pharmacological functions, resveratrol and its oligomers are now gaining scientific attention as a longevity promoter.
Vatica mangachapoi, a large and rather rare species, occurs only in Hainan Island in China and is used as a...
This work was supported by the Program for Innovative Research Team in University (No. IRT-16R19), Natural Science Foundation of Hainan Province (No. 20152036), and Science and Technology Project of Social Development of Hainan Province (Nos. 2015SF36, ZDYF2016139).
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