Chemistry of Natural Compounds

, Volume 54, Issue 5, pp 975–977 | Cite as

Flavanones and Flavones from Bashkir Propolis

  • R. A. ZainullinEmail author
  • R. V. Kunakova
  • V. F. Gareev
  • I. V. Galyautdinov
  • Z. R. Sadretdinova
  • Z. S. Muslimov
  • V. N. Odinokov

Propolis is a product of the honey bee Apis mellifera and has a broad spectrum of biological activity (antimicrobial, antifungal, antitumor, antineurodegenerative, anti-inflammatory, antioxidant, cytotoxic, antituberculosis, antiviral, and immunomodulating [1]) that is widely employed in traditional [2, 3] and folk medicine [4].

Greater than 500 compounds [5], of which more than 150 were flavonoids [6], were identified in the constituents of propolis depending on the geographic location, bee species, and plants.

The chemical composition of Bashkir propolis produced by A. mellifera from plants of the southern Urals (Bashkiria) was studied by us for the first time. Pure flavanones 14 and flavones 5 and 6 were isolated and identified.



The work was financially supported by the Russian Foundation for Basic Research and the Academy of Sciences of the Republic of Bashkortostan (Project No. 17-43-020483 p_a). Structures of compounds were established using PMR and 13C NMR spectra with 2D experiments (COSY, HSQC, HMBC, NOESY) and MALDI TOF/TOF mass spectra obtained at the Agidel Common Use Center at the IPC, RAS.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • R. A. Zainullin
    • 1
    Email author
  • R. V. Kunakova
    • 1
  • V. F. Gareev
    • 1
  • I. V. Galyautdinov
    • 2
  • Z. R. Sadretdinova
    • 2
  • Z. S. Muslimov
    • 2
  • V. N. Odinokov
    • 2
  1. 1.Ufa State Petroleum Technological UniversityUfaRussia
  2. 2.Institute of Petrochemistry and CatalysisRussian Academy of SciencesUfaRussia

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