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Chemistry of Natural Compounds

, Volume 54, Issue 5, pp 970–972 | Cite as

Triterpenes, Flavonoids, and Lignans from Dracocephalum heterophyllum

  • Qiang-qiang Shi
  • Jian-qiang Zhao
  • Jun Dang
  • Xiang Yuan
  • Qi-lan Wang
Article
  • 35 Downloads

Dracocephalum heterophyllum (Labiatae) is a traditional Tibetan medicine growing on the Qinghai-Tibet Plateau in a special living environment of high elevation and strong sunlight irradiation. The plant is distributed widely in Sitsang, Qinghai, Sinkiang, and Gansu Provinces of China. In traditional Tibetan Medicine, D. heterophyllum is known as “Ao-Ga” or “Ji-Mei-Qing-Bao,” which has been used as an ethnomedicine to treat various ailments such as jaundice, hepatopathy, cough, lymphangitis, mouth ulcers, and tooth diseases. There are reports that the herb possesses antiviral activity [1], anti-anoxic effect [2], anti-asthma, anti-coughing, and disinfectant action [3]. The chemical composition of the volatile oil of D. heterophyllum has been reported [4]. The present work reports the nonvolatile components of D. heterophyllum. Fourteen different compounds were found in this plant that contain triterpenes, flavonoids, lignans, and some other compounds. It is suggested that triterpenes...

Notes

Acknowledgment

The authors gratefully appreciate support from Senior Engineer Li-Juan Mei from the Northwest Institute of Plateau Biology, CAS, who helped us to identify the authenticity of D. heterophyllum. The authors also like to thank the grant support from the advanced technology research and development program of Qinghai Province (2014-GX-220).

References

  1. 1.
    C. J. Zhang, W. Li, H. Y. Li, Y. L. Wang, T. Yun, Z. P. Song, Y. Song, and X. W. Zhao, Pharm. Biol., 47, 598 (2009).CrossRefGoogle Scholar
  2. 2.
    H. F. Peng, Med. J. Chin. People’s Liberation Army, 2 (1984).Google Scholar
  3. 3.
    U. Mahmood, V. K. Kaul, V. Singh, Brij Lal, H. R. Negi, and P. S. Ahuja, Flav. Frag. J., 20, 173 (2005).CrossRefGoogle Scholar
  4. 4.
    C. J. Zhang, H. Y. Li, T. Yun, Y. H. Fu, C. M. Liu, B. Gong, and B. J. Neng, Nat. Prod. Res., 22, 1 (2008).CrossRefGoogle Scholar
  5. 5.
    G. Chen, H. Ren, and C. Yu, Chem. Nat. Compd., 47, 918 (2012).CrossRefGoogle Scholar
  6. 6.
    T. P. Kukina, T. S. Frolova, and O. I. Salnikova, Chem. Nat. Compd., 50, 233 (2014).CrossRefGoogle Scholar
  7. 7.
    H. X. Kuang, R. Kasai, K. Ohtani, Z. S. Liu, C. S. Yuan, and O. Tanaka, Chem. Pharm. Bull., 37, 2232 (1989).CrossRefGoogle Scholar
  8. 8.
    O. Baris, M. Karadayi, D. Yanmis, Z. Guvenalp, T. Bal, and M. Gulluce, J. Food Sci., 76, T212 (2011).CrossRefGoogle Scholar
  9. 9.
    Abdallah A. Omar, Taha M. Sarg, Saad M. Khafagy, Yousef E. Ibrahim, and Michael Grenz, Phytochemistry, 23, 2381 (1984).CrossRefGoogle Scholar
  10. 10.
    J. Kitajima, T. Ishikawa, Y. Tanaka, M. Ono, Y. Ito, and T. Nohara, Chem. Pharm. Bull., 46, 1587 (1998).CrossRefGoogle Scholar
  11. 11.
    S. Liu, Z. Zheng, G. Zheng, L. Chen, T. Zhong, and Y. Ming, Chem. Nat. Compd., 51, 844 (2015).CrossRefGoogle Scholar
  12. 12.
    Z. S. Akdemir, Tatli, II, E. Bedir, and I. A. Khan, Turk. J. Chem., 28, 621 (2004).Google Scholar
  13. 13.
    A. N. Binns, R. H. Chen, H. N. Wood, and D. G. Lynn, Proc. Natl. Acad. Sci. USA, 84, 980 (1987).CrossRefGoogle Scholar
  14. 14.
    C. Z. Wang and Z. J. Jia, Phytochemistry, 45, 159 (1997).CrossRefGoogle Scholar
  15. 15.
    Q. Hu, H. Mu, H. Huang, H. Lv, S. Li, and G. Yang, Chem. Nat. Compd., 48, 198 (2012).CrossRefGoogle Scholar
  16. 16.
    S. Aziz, M. Irshad, and R. Habib ur, Chem. Nat. Compd., 49, 1023 (2014).CrossRefGoogle Scholar
  17. 17.
    H. Y. Xu, G. G. Hu, J. Dong, Q. Wei, H. B. Shao, and M. Lei, Sci. World J., 2014, 857982 (2014).Google Scholar
  18. 18.
    H. Geiger, A. Voigt, T. Seeger, H. D. Zinsmeister, J. A. Lopezsaez, M. J. Perezalonso, and A. Velasconegeruela, Phytochemistry, 39, 465 (1995).CrossRefGoogle Scholar
  19. 19.
    S. Niranjan, A. Basudeb, and B. Sukdeb, Phytochemistry, 49, 1425 (1998).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Qiang-qiang Shi
    • 1
    • 2
  • Jian-qiang Zhao
    • 1
    • 2
  • Jun Dang
    • 1
  • Xiang Yuan
    • 1
    • 2
  • Qi-lan Wang
    • 1
  1. 1.Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau BiologyChinese Academy of SciencesXiningP. R. China
  2. 2.University of Chinese Academy of ScienceBeijingP. R. China

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