Fatty Acids from Fritillaria pallidiflora and Their Biological Activity
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The perennial herbaceous plant Fritillaria pallidiflora Schrenk (Liliaceae) is distributed mainly in Xinjiang Province of the PRC. Bulbs of F. pallidiflora have been used in folk medicine for a long time as antiasthmatic, anticough, and cholegogic agents . Previously, isosteroidal alkaloids, glycosides, coumarins, and terpenoids were isolated from the plant [2, 3, 4].
Herein, results from gas-chromatography–mass-spectrometry (GC-MS) studies of the fatty-acid composition of dry bulbs of F. pallidiflora are reported for the first time. Dried and ground bulbs (100 g) were extracted with petroleum ether (500 mL) at 80°C in a Soxhlet apparatus. The solvent was evaporated to afford the final residue (1.04 g).
IR spectra of the petroleum-ether extract of F. pallidiflora showed characteristic absorption bands in the ranges 3000–3416 (OH), 2920 and 2851 (CH2 and CH3), 1742 and 1646 (C=O), and 1169 and 1049 cm–1 (C–O).
Methylation used the following method. Petroleum-ether extract (100 mg)...
The work was financially supported by a Program of the Chinese National Natural Science Foundation (No. U1403201).
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