Chemistry of Natural Compounds

, Volume 54, Issue 1, pp 137–141 | Cite as

Diterpenoid Alkaloids from Aconitum brachypodum

  • Xianyou Wang
  • Dongxiao Wang
  • Guofang Lai
  • Zhihong Zhou
  • Yifen Wang

Three new C-19 diterpene alkaloids, along with two known ones, were isolated from the roots of Aconitum brachypodum Diels. The structures of the new alkaloids were established as N-deethyl-3-Oacetylchasmaconitine (1), N-deethyl-3-O-acetylyunaconitine (2), and N-deethyl-3-O-acetyljesaconitine (3). Their structures were elucidated by extensive spectroscopic methods, including 1D (1H, 13C) NMR and 2D NMR (1H–1H COSY, TOCSY, ROESY, HSQC, and HMBC) experiments, as well as high-resolution electrospray ionization mass spectrometry (HR-ESI-MS).


C-19 diterpenoid alkaloid Aconitum brachypodum 



The authors are grateful to the Analytical Center of the Chemistry College of Henan University for measuring NMR, MS, and IR data.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Pharmaceutical College of Henan UniversityKaifengPeople’s Republic of China
  2. 2.Yunnan University of TCMYunnanPeople’s Republic of China
  3. 3.State Key Laboratory of Photochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of SciencesKunmingPeople’s Republic of China
  4. 4.Yunnan Institute for Food and Drug ControlKunmingPeople’s Republic of China

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