Constituents of Convolvulus fruticosus and Pharmacological Activity of the Main Alkaloid Cuscohygrine
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Plants of the genus Convolvulus (Convolvulaceae) are broadly distributed in the world and number over 190 species , 18 of which grow in the Central Asia.
The species C. fruticosus Pall. occurs in Fergana, Bukhara, and Surxondaryo (Kashkadarya River basin) Oblasts and Karakalpakstan . The contents of coumarins, flavonoids, saponins, lactones, tanning agents, and essential oil from C. fruticosus collected in Turkmenistan have been reported .
We have established for the first time the alkaloid composition of C. fruticosus collected during flowering in Bukhara Oblast (Kuljuktau). Dried and ground aerial parts of the plant (2 kg) were extracted with CHCl3 by the usual method for alkaloids  to afford total alkaloids (0.08%). TLC (KSK silica gel) of the obtained mixture of bases (1.6 g) using system 1 (CHCl3–MeOH, 3.5:1.5) detected five compounds. The compound with Rf0.1 was identified as tropine by comparison with an authentic sample. Cuscohygrine (base, 0.2 g, light-yellow...
KeywordsAlkaloid Cytisine Total Alkaloid Tropane Barium Chloride
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