Chemistry of Natural Compounds

, Volume 50, Issue 1, pp 88–92 | Cite as

Phenolic Compounds from Monomeria barbata

  • Minghui Yang
  • Le Cai
  • Haixian Fang
  • Shengchun Yang
  • Yunshan Fang
  • Zhongtao Ding
Article
First Online:
Received:

A new 9,10-dihydrophenanthrene derivative, monbarbatain E (1), together with 10 known bibenzyl or phenanthrene derivatives, were isolated from the acetone extract of the rhizomes of Monomeria barbata Lindl. The new compound was identified as 4-O-[4″-(5′-hydroxy-3′,3″-dimethoxybibenzyl)]-1,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene on the basis of extensive spectroscopic investigations (HR-ESI-MS, 1D and 2D NMR). Compounds 1 and 2 were evaluated for their cytotoxic effects, and compounds 2–5 were tested for their antioxidant activities. Compounds 1 and 2 exhibited medium cytotoxic activity against HL-60 and Skov-3 cell lines. Compounds 2–5 showed significant DPPH radical scavenging activities.

Keywords

Monomeria barbata Lindl dihydrophenanthrene phenolic compounds cytotoxic activity DPPH radical scavenging activity 
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Notes

Acknowledgment

This work was supported by the programs from the National Nature Science Foundation of China (Nos. 20964005, 81160393, and 21002084) and a grant from the Nature Science Foundation of Yunnan Province (No. 2010CD017).

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Minghui Yang
    • 1
    • 2
  • Le Cai
    • 1
  • Haixian Fang
    • 1
  • Shengchun Yang
    • 2
  • Yunshan Fang
    • 1
  • Zhongtao Ding
    • 1
  1. 1.Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and TechnologyYunnan UniversityKunmingP. R. China
  2. 2.School of Pharmaceutical Sciences and ChemistryDali UniversityDaliP. R. China

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