Structure elucidation and NMR assignments for two new quinones from fructus rhodomyrti of Rhodomyrtus tomentosa
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Two new quinones, 1,4,7-trihydroxy-2-methoxy-6-methylanthracene-9,10-dione (1) and compound 2, were isolated from fructus rhodomyrti of Rhodomyrtus tomentosa (Ari.) Hassk., which was collected from Guangdong Province. The structures were elucidated by 1D, 2D NMR, and HR-EI-MS spectroscopy methods. The cytotoxic activities of two compounds in vitro were tested. Compound 1 showed cytotoxicity against KB and KBv200 cell lines with IC50 of 17.1 and 19.5 )μg/mL, and compound 2 with IC50 of 18.1 and 25.4 )μg/mL, respectively.
KeywordsNMR fructus rhodomyrti quinone structure elucidation cytotoxic activity
This work was supported by the Natural Science Foundation of Guangdong Province of China (63116).