Chemistry of Natural Compounds

, Volume 46, Issue 5, pp 756–759 | Cite as

bis-Cardenolides

Article
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Twelve new bis-cardenolides were synthesized by reaction of natural cardenolides with diamines to form imines and ammonium salts. Anomalous physicochemical properties consisting of resistance to hydrolysis and increased polarity were observed for the bis-ketoimines.

Keywords

strophanthidine strophanthidinic acid strophanthidine-19-carboxylic acid digitoxigenone strophanthidine imines digitoxigenone imines strophanthidinic acid ammonium salts 

References

  1. 1.
    I. F. Makarevich, Yu. I. Gubin, and R. Megges, Khim. Prir. Soedin., 42 (2005).Google Scholar
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    I. F. Makarevich, Yu. I. Gubin, and R. Megges, Khim. Prir. Soedin., 268 (2005).Google Scholar
  3. 3.
    I. F. Makarevich and Yu. I. Gubin, in: 6th International Symposium on the Chemistry of Natural Compounds (SCNC), June 28-29, 2005, Ankara, Turkey, 2005, p. 83.Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  1. 1.National Pharmaceutical UniversityKharkovUkraine

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