Chemistry of Natural Compounds

, Volume 45, Issue 6, pp 811–813

A novel bromophenol from marine red alga Symphyocladia latiuscula

  • Xiuli Xu
  • Fuhang Song
  • Xiao Fan
  • Nianqiao Fang
  • Jiangong Shi
Article

2,3,6-Tribromo-4,5-dihydroxybenzyl ethyl ether (1), a new bromophenol, was isolated from the ethanol extract of marine red alga Symphyocladia latiuscula, with a known compound, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether (2). Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1 and 2-dimensional NMR techniques. Compounds 1 and 2 showed inhibitory activity against Staphyloccocus aureus with IC50 102 and 50 μg/mL, respectively.

Key words

Symphyocladia latiuscula bromophenol Staphyloccocus aureus 

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • Xiuli Xu
    • 1
  • Fuhang Song
    • 2
  • Xiao Fan
    • 3
  • Nianqiao Fang
    • 1
  • Jiangong Shi
    • 4
  1. 1.School of Marine ScienceChina University of GeosciencesBeijingP. R. China
  2. 2.Institute of MicrobiologyChinese Academy of SciencesBeijingP. R. China
  3. 3.Institute of OceanologyChinese Academy of SciencesQingdaoP. R. China
  4. 4.Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingP. R. China

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