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Chemistry of Natural Compounds

, 45:720 | Cite as

Antibacterial activity of the chemical constituents from Ranunculus laetus

  • Javid Hussain
  • Hidayat Hussain
  • Zabta Khan Shinwari
  • Ijaz Ahmad
  • S. Tasleem Hussain
  • Viqar Uddin Ahmad
Article

The genus Ranunculus belongs to the family Ranunculaceae, which comprises 50 genera and 2000 species, distributed throughout the northern hemisphere. It is also found in southern temperate regions in the tropics where they are usually confined to higher altitudes. In Pakistan, it is represented by 22 genera and about 114 species, of which several genera are of ornamental value while the others are toxic and used for medicinal purposes [1].

The plant Ranunculus laetus was collected from the Parachinar Kurram Agency, Pakistan, in April-May 2001, and was identified by Dr. Jahandar Shah (plant taxonomist) at the Department of Botany, University of Peshawar, Pakistan. The chloroform extract (86 g) was subjected to column chromatography using different solvent systems. The eluent obtained with n-hexane–CHCl3 (8:2, v/v), was again subjected to silica gel column chromatography to obtain compounds 16. These compounds were three known flavone jacein (1) [2], jacedin-5-O-β-D-glucoside (2) [3],...

Keywords

MeOH CHCl3 Antibacterial Activity Coumarin Pseudomonas Aeruginosa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • Javid Hussain
    • 1
  • Hidayat Hussain
    • 2
  • Zabta Khan Shinwari
    • 3
  • Ijaz Ahmad
    • 1
  • S. Tasleem Hussain
    • 1
  • Viqar Uddin Ahmad
    • 4
  1. 1.Department of Chemistry Kohat University of Science and TechnologyKohatPakistan
  2. 2.Departments of ChemistryUniversity PaderbornPaderbornGermany
  3. 3.Department of Plant SciencesQuaid-i-Azam UniversityIslamabadPakistan
  4. 4.International Center for Chemical and Biological Sciences, H. E. J. Research Institute of ChemistryUniversity of KarachiKarachiPakistan

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