Flavonoid aglycones of Oxytropis falcata
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Oxytropis falcata is a wild growing Leguminosae plant distributed mainly in the Qinghai-Tibet Plateau in China. The herb of this plant has been known as one of the “Three Anti-inflammatory Drugs” and “King of Herbs” in Chinese Tibetan medicine, and been used to treat inflammation, nociception, pyreticosis, and bleeding for thousands of years [1, 2]. At present, there are many Chinese traditional patent prescriptions that include this medicine in the market. However, there is still only little information on the phytochemistry [3, 4, 5] and pharmacological actions of OFB [6, 7, 8].
This report describes the isolation from Oxytropis falcataof 2′,4′-dihydroxydihydrochalcone, 2′-methoxy-4′hydroxychalcone, 2′-hydroxy-4′-methoxychalcone, 2′,4′-dihydroxychalcone, isoliquiritigenin, pinostrobin, pinocembrin, 7-hydroxyflavonone, liquiritigenin, kaempferol, isorhamnetin, quercetin, myricetin, chrysin, apigenin, and luteolin, and the structure elucidation of these crystalline substances by...
KeywordsQuercetin EtOH EtOAc Kaempferol Luteolin
The spectra of compounds were measured by Dr. Shen Wenbin, China Pharmaceutical University.
The work was sponsored by the Scientific Research Foundation for Returning Overseas Chinese Scholars (z2006-1-81003), State Education Ministry.
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