Eligibility, Recruitment, and Retention of African Americans with Severe Mental Illness in Community Research
- 166 Downloads
Data that addresses severely mentally ill (SMI) African Americans (AAs) likelihood to participate in clinical research is limited. This study’s purpose was to determine if differences exist between races regarding eligibility, recruitment, and retention in a community-based clinical trial. The sample included 293 participants. Data sources included clinical records and interviews. Logistic regression was used for analysis. AAs were as likely to participate and to complete followup interviews as Whites. In contrast to studies about non-mentally ill AAs, AAs with SMI appeared to be as willing to consent to and to remain in clinical research studies as Whites.
KeywordsAfrican American Recruitment Retention Severe mental illness
This work was funded by grants from the National Institutes of Health, National Institute of Nursing Research (R01 NR05350 and NR005350-4, Research Supplement for Underrepresented Minorities), and the Substance Abuse and Mental Health Services Administration (Minority Fellowship Program).
- Barrio, C., Yamada, A. M., Atuel, H., Hough, R. L., Yee, S., Berthot, B., et al. (2003). A tri-ethnic examination of symptom expression on the positive and negative syndrome scale in schizophrenia-spectrum disorders. Schizophrenia Research, 60(2–3), 259–269. doi: 10.1016/S0920-9964(02)00223-2.PubMedCrossRefGoogle Scholar
- Chung, H., Mahler, J. C., & Kakuma, T. (1995). Racial differences in treatment of psychiatric inpatients. Psychiatric Services (Washington, DC), 46(6), 586–591.Google Scholar
- Connell, C. M., Shaw, B. A., Holmes, S. B., & Foster, N. L. (2001). Caregivers’ attitudes toward their family members’ participation in Alzheimer disease research: Implications for recruitment and retention. Alzheimer Disease and Associated Disorders, 15(3), 137–145. doi: 10.1097/00002093-200107000-00005.PubMedCrossRefGoogle Scholar
- Durant, R. W., Davis, R. B., St George, D. M., Williams, I. C., Blumenthal, C., & Corbie-Smith, G. M. (2007). Participation in research studies: Factors associated with failing to meet minority recruitment goals. Annals of Epidemiology, 17(8), 634–642. doi: 10.1016/j.annepidem.2007.02.003.PubMedCrossRefGoogle Scholar
- Gilliss, C. L., Lee, K. A., Gutierrez, Y., Taylor, D., Beyene, Y., Neuhaus, J., et al. (2001). Recruitment and retention of healthy minority women into community-based longitudinal research. Journal of Women’s Health & Gender-Based Medicine, 10(1), 77–85. doi: 10.1089/152460901750067142.CrossRefGoogle Scholar
- Gooden, K. M., Carter-Edwards, L., Hoyo, C., Akbar, J., Cleveland, R. J., Oates, V., et al. (2005). Perceptions of participation in an observational epidemiologic study of cancer among African Americans. Ethnicity & Disease, 15(1), 68–75.Google Scholar
- Hessol, N. A., Schneider, M., Greenblatt, R. M., Bacon, M., Barranday, Y., Holman, S., et al. (2001). Retention of women enrolled in a prospective study of human immunodeficiency virus infection: Impact of race, unstable housing, and use of human immunodeficiency virus therapy. American Journal of Epidemiology, 154(6), 563–573. doi: 10.1093/aje/154.6.563.PubMedCrossRefGoogle Scholar
- Lehman, A. F. (2000). The quality of life interview. In Handbook of psychiatric measures (pp. 138–140). Washington, DC: American Psychiatric Association.Google Scholar
- McLellan, A. T. (2000). Addiction severity index (ASI). In Handbook of psychiatric measures (pp. 472–474). Washington, DC: American Psychiatric Association.Google Scholar
- National Institutes of Health. (NIH) (October 1, 2001). NIH policy and guidelines on the inclusion of women and minorities as subjects in clinical research. http://grants.nih.gov/grants/funding/women_min/guidelines_amended_10_2001.htm. Retrieved 5 Nov 2007.
- Neighbors, H. W., Trierweiler, S. J., Ford, B. C., & Muroff, J. R. (2003). Racial differences in DSM diagnosis using a semi-structured instrument: The importance of clinical judgment in the diagnosis of African Americans. Journal of Health and Social Behavior, 44(3), 237–256. doi: 10.2307/1519777.PubMedCrossRefGoogle Scholar
- Riedel, M., Strassnig, M., Muller, N., Zwack, P., & Moller, H. J. (2005). How representative of everyday clinical populations are schizophrenia patients enrolled in clinical trials? European Archives of Psychiatry and Clinical Neuroscience, 255(2), 143–148. doi: 10.1007/s00406-004-0547-5.PubMedCrossRefGoogle Scholar
- Thompson, E. E., Neighbors, H. W., Munday, C., & Jackson, J. S. (1996). Recruitment and retention of African American patients for clinical research: An exploration of response rates in an urban psychiatric hospital. Journal of Consulting and Clinical Psychology, 64(5), 861–867. doi: 10.1037/0022-006X.64.5.861.PubMedCrossRefGoogle Scholar
- Trierweiler, S. J., Neighbors, H. W., Munday, C., Thompson, E. E., Binion, V. J., & Gomez, J. P. (2000). Clinician attributions associated with the diagnosis of schizophrenia in African American and non-African American patients. Journal of Consulting and Clinical Psychology, 68(1), 171–175. doi: 10.1037/0022-006X.68.1.171.PubMedCrossRefGoogle Scholar