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Chemistry of Heterocyclic Compounds

, Volume 54, Issue 10, pp 905–922 | Cite as

Stabilized azomethine ylides derived from indeno[1,2-b]quinoxalinones in [3+2] cycloaddition reactions with electrophilic alkenes

  • Vladislav Yu. Korotaev
  • Nikolay S. Zimnitskiy
  • Alexey Yu. Barkov
  • Igor B. Kutyashev
  • Vyacheslav Ya. Sosnovskikh
REVIEW
  • 75 Downloads

We provide a general and systematic review of all currently published data on the use of stabilized azomethine ylides derived from 11H-indeno[1,2-b]quinoxalin-11-one and 6H-indeno[1,2-b]pyrido[3,2-e]pyrazin-6-one in the synthesis of spiropyrrolidines and spiropyrrolizidines. The reaction conditions, as well as the regio- and stereoselectivity of the [3+2] cycloaddition process are discussed. Data on the biological activity of the obtained products are presented. There are 62 literature references.

Keywords

6H-indeno[1,2-b]pyrido[3,2-e]pyrazin-6-one 11H-indeno[1,2-b]quinoxalin-11-one electrophilic alkenes stabilized azomethine ylides biological activity 1,3-dipolar cycloaddition multicomponent reactions 

Notes

This work was performed with financial support from the Ministry of Education and Science of the Russian Federation (contract 02.A03.21.0006) and the Russian Foundation for Basic Research (project No. 18-33-00635).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Vladislav Yu. Korotaev
    • 1
  • Nikolay S. Zimnitskiy
    • 1
  • Alexey Yu. Barkov
    • 1
  • Igor B. Kutyashev
    • 1
  • Vyacheslav Ya. Sosnovskikh
    • 1
  1. 1.Institute of Natural Sciences and MathematicsUral Federal University named after the first President of Russia B. N. YeltsinYekaterinburgRussia

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