Chemistry of Heterocyclic Compounds

, Volume 52, Issue 12, pp 996–998

Synthesis of β-carbolines (microreview)

HETEROCYCLES IN FOCUS
  • 122 Downloads
Open image in new window β-Carbolines are an important class of heterocyclic compounds because of their broad spectrum of biological profiles. Consequently, many methodologies have been described to construct the β-carboline scaffold. This microreview summarizes these newly developed synthetic approaches.

References

  1. 1.
    Love, B. E. Org. Prep. Proced. Int. 1996, 28, 1.CrossRefGoogle Scholar
  2. 2.
    Domínguez, G.; Pérez-Castells, J. Eur. J. Org. Chem. 2011, 7243.Google Scholar
  3. 3.
    Singh, V.; Batra, S. Curr. Org. Synth. 2012, 9, 513.CrossRefGoogle Scholar
  4. 4.
    McNulty, J.; Still, I. W. J. Curr. Org. Chem. 2000, 4, 121.CrossRefGoogle Scholar
  5. 5.
    Menna, M.; Fattorusso, E.; Imperatore, C. Molecules 2011, 16, 8694.CrossRefGoogle Scholar
  6. 6.
    Rosillo, M.; González-Gómez, A.; Domínguez, G.; Pérez-Castells, J. Targets Heterocycl. Syst. 2008, 12, 212.Google Scholar
  7. 7.
    Ashok, P.; Ganguly, S.; Murugesan, S. Mini. Rev. Med. Chem. 2013, 13, 1778.CrossRefGoogle Scholar
  8. 8.
    Laine, A. E.; Lood, C.; Koskinen, A. M. P. Molecules 2014, 19, 1544.CrossRefGoogle Scholar
  9. 9.
    Zhang, M.; Sun, D. Anti-Cancer Agents Med. Chem. 2015, 15, 537.CrossRefGoogle Scholar
  10. 10.
    Stöckigt, J.; Antonchick, A. P.; Wu, F.; Waldmann, H. Angew. Chem., Int. Ed. 2011, 50, 8538.Google Scholar
  11. 11.
    Heravi, M. M.; Nazari, N. Curr. Org. Chem. 2015, 19, 2358.CrossRefGoogle Scholar
  12. 12.
    Ding, S.; Shi, Z.; Jiao, N. Org. Lett. 2010, 12, 1540.CrossRefGoogle Scholar
  13. 13.
    Shi, Z.; Cui, Y.; Jiao, N. Org. Lett. 2010, 12, 2908. 14. Verniest, G.; England, D.; De Kimpe, N.; Padwa, A. Tetrahedron 2010, 66, 1496.Google Scholar
  14. 14.
    Verniest, G.; England, D.; De Kimpe, N.; Padwa, A. Tetrahedron 2010, 66, 1496.CrossRefGoogle Scholar
  15. 15.
    Yang, Y.-F.; Li, L.-H.; He, Y.-T.; Luo, J.-Y.; Liang, Y.-M. Tetrahedron 2014, 70, 702.CrossRefGoogle Scholar
  16. 16.
    Nissen, F.; Richard, V.; Alayrac, C.; Witulski, B. Chem. Commun. 2011, 47, 6656.CrossRefGoogle Scholar
  17. 17.
    Pumphrey, A. L.; Dong, H.; Driver, T. G. Angew. Chem., Int. Ed. 2012, 51, 5920.Google Scholar
  18. 18.
    Mulcahy, S. P.; Varelas, J. G. Tetrahedron Lett. 2013, 54, 6599.CrossRefGoogle Scholar
  19. 19.
    Verlas, J. G.; Khanal, S.; O'Donnell, M. A.; Mulcahy, S. P. Org. Lett. 2015, 17, 5512.CrossRefGoogle Scholar
  20. 20.
    Kamlah, A.; Lirk, F.; Bracher, F. Tetrahedron, 2016, 72, 837.CrossRefGoogle Scholar
  21. 21.
    Shang, H.; Tian, Y.; Luo, J.; Li, L.; Tang, Y.; Zou, Z. RSC Adv. 2016, 6, 30835.CrossRefGoogle Scholar
  22. 22.
    Dhara, S.; Singha, R.; Ahmed, A.; Mandal, H.; Ghosh, M.; Nuree, Y.; Ray, J. K. RSC Adv. 2014, 4, 45163.CrossRefGoogle Scholar
  23. 23.
    Dhiman, S.; Mishra, U. K.; Ramasastry, S. S. V. Angew. Chem., Int. Ed. 2016, 55, 7737.Google Scholar
  24. 24.
    Song, H.; Liu, Y.; Wang, Q. Org. Lett. 2013, 15, 3274.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Directorate of Drug Substance DevelopmentEgis Pharmaceuticals PlcBudapestHungary
  2. 2.Institute of Organic Chemistry, Research Centre for Natural SciencesHungarian Academy of SciencesBudapestHungary

Personalised recommendations