Chemistry of Heterocyclic Compounds

, Volume 48, Issue 3, pp 427–435 | Cite as

Synthesis of 3-substituted 2-amino-1-hydroxy-1H-indole-5,6-dicarbonitriles

  • S. I. Filimonov
  • Zh. V. Chirkova
  • V. S. Sharunov
  • I. G. Abramov
  • G. A. Stashina
  • S. I. Firgang
  • K. Yu. Suponitsky
Article
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A method of synthesizing new 3-substituted 2-amino-1-hydroxy-1H-indole-5,6-dicarbonitriles has been developed based on the reductive cyclization of substituted 4-cyanomethyl-5-nitrophthalonitriles.

Keywords

2,1-benzisoxazoles 1-hydroxy-1H-indole-5,6-dicarbonitriles phthalonitriles C-nucleophi-lic substitution reductive cyclization 
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Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  • S. I. Filimonov
    • 1
  • Zh. V. Chirkova
    • 1
  • V. S. Sharunov
    • 1
  • I. G. Abramov
    • 1
  • G. A. Stashina
    • 2
  • S. I. Firgang
    • 2
  • K. Yu. Suponitsky
    • 3
  1. 1.Yaroslavl State Technical UniversityYaroslavlRussia
  2. 2.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia
  3. 3.A. N. Nesmeyanov Institute of Organoelement CompoundsRussian Academy of SciencesMoscowRussia

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