Chemistry of Heterocyclic Compounds

, Volume 48, Issue 1, pp 33–38 | Cite as

Multicomponent reactions in alkaloid-based drug discovery

  • I. V. Magedov
  • A. Kornienko

Multicomponent reactions are emerging as a powerful tool in alkaloid-based drug discovery. This highlight describes several recent (all published in 2011) examples of the employment of multicomponent reactions for the synthesis of biologically active alkaloids and their medicinally relevant analogs.


alkaloid cyanocycline A luotonin rigidin tubulysin drug discovery multicomponent reactions 


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Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  1. 1.New Mexico Institute of Mining and TechnologySocorroUSA

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