Chemistry of Heterocyclic Compounds

, Volume 47, Issue 7, pp 826–832

4-hydroxy-2-quinolones. 197*. The search for novel diuretics amongst halo-substituted 6-hydroxy-2-methyl-4-oxo-1,2-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid anilides

  • I. V. Ukrainets
  • N. Yu. Golik
  • A. L. Shemchuk
  • O. I. Naboka
  • Yu. V. Voronina
  • A. V. Turov
Article

DOI: 10.1007/s10593-011-0842-9

Cite this article as:
Ukrainets, I.V., Golik, N.Y., Shemchuk, A.L. et al. Chem Heterocycl Comp (2011) 47: 826. doi:10.1007/s10593-011-0842-9

A targeted synthesis of a series of halo-substituted 6-hydroxy-2-methyl-4-oxo-1,2-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid anilides have been carried out. Peculiarites of the 1H NMR spectra and the results of investigating the diuretic activity of these compounds are discussed.

Keywords

anilides 4-hydroxy-2-oxoquinoline-3-carboxylic acids methylindoline amidation diuretic activity 

Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • I. V. Ukrainets
    • 1
  • N. Yu. Golik
    • 1
  • A. L. Shemchuk
    • 1
  • O. I. Naboka
    • 1
  • Yu. V. Voronina
    • 1
  • A. V. Turov
    • 2
  1. 1.National University of PharmacyKharkivUkraine
  2. 2.Taras Shevchenko National UniversityKyivUkraine

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