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Chemistry of Heterocyclic Compounds

, Volume 43, Issue 4, pp 490–495 | Cite as

Interaction of aminoazoles with Meldrum’s acid and dialkyl ketones or cyclohexanone

  • V. V. Lipson
  • V. V. Borodina
  • M. G. Shirobokova
  • S. M. Desenko
  • O. V. Shishkin
  • R. I. Zubatyuk
Article

Abstract

Interaction of 3-amino-5-methylpyrazole, 3-amino-5-methylthio-, and 3,5-diamino-1,2,4-triazole with Meldrum’s acid, acetone, ethyl methyl ketone, and cyclohexanone leads to alkyl-substituted pyrazolo[3,4-b]pyridin-6-ones and 1,2,4-triazolo[1,5-a]pyrimidin-7-ones respectively. The structure of 5,5-dimethyl-2-methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-7-one was demonstrated by an X-ray structural investigation.

Keywords

3-amino-5-methylpyrazole 3-amino-5-methylthio-1,2,4-triazole dialkyl ketones 3,5-diamino-1,2,4-triazole Meldrum’s acid pyrazolo[3,4-b]pyridin-6-ones 1,2,4-triazolo[1,5-a]pyrimidin-7-ones X-ray structural analysis 

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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • V. V. Lipson
    • 1
  • V. V. Borodina
    • 1
  • M. G. Shirobokova
    • 1
  • S. M. Desenko
    • 2
  • O. V. Shishkin
    • 2
  • R. I. Zubatyuk
    • 2
  1. 1.V. Ya. Danilevsky Institute of Endocrine Pathology ProblemsAcademy of Medical Sciences of UkraineKharkiv
  2. 2.Institute of Single CrystalsNational Academy of Sciences of UkraineKharkiv

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