A new method for the partition of allelic diversity within and between subpopulations
- 206 Downloads
A method is proposed for the analysis of allelic diversity in the context of subdivided populations. The definition of an allelic distance between subpopulations allows for the partition of total allelic diversity into within- and between-subpopulation components, in a way analogous to the classical partition of gene diversity. A new definition of allelic differentiation, A ST , between subpopulations results from this partition, and is contrasted with the concept of allelic richness differentiation. The partition of allelic diversity makes it possible to establish the relative contribution of each subpopulation to within and between-subpopulation components of diversity with implications in priorisation for conservation. A comparison between this partition and that corresponding to allelic richness is illustrated with an example. Computer simulations are used to investigate the behaviour of the new statistic A ST in comparison with F ST for a finite island model under a range of mutation and migration rates. A ST has less dependence on migration rate than F ST for large values of migration rate, but the opposite occurs for low migration rates. In addition, the variance in the estimates of A ST is higher than that of F ST for low mutation rates, but the opposite for high mutation rates.
KeywordsAllelic diversity Gene diversity Heterozygosity Rarefaction Conservation priorities
We thank L. Ollivier, J. L. Foulley, J. Fernández, M. A. Toro and three referees for useful comments on the manuscript. This work was funded by Ministerio de Ciencia y Tecnología and Fondos Feder (CGL2006-13445-C02/BOS and CGL2009-13278-C02), and Xunta de Galicia.
- Crow FJ, Kimura M (1970) An introduction to population genetics theory. Harper & Row, New YorkGoogle Scholar
- Kimura M Crow JF (1964) The number of alleles that can be maintained in a finite population. Genetics 49:725–738Google Scholar
- Ollivier L, Foulley JL (2009) Managing genetic diversity, fitness and adaptation of farm animal genetic resources. In: van der Werf J, Graser H-U, Frankham R, Gondro C (eds) Adaptation and fitness in animal populations—evolutionary and breeding perspectives on genetic resource management. Springer, Dordrecht, pp 201–227Google Scholar
- Rodrigáñez J, Barragán C, Alves E, Cortázar C, Toro MA (2008) Genetic diversity and allelic richness in Spanish wild and domestic pig population estimated from microsatellite markers. Span J Agric Res 1:107–115Google Scholar
- Tapio I, Varv S, Bennewitz J, Maleviciute J, Fimland E, Grislis Z, Meuwissen THE, Miceikiene I, Olsaker I, Viinalass H, Vilkki J, Kantanen J (2006) Prioritization for conservation of northern European cattle breeds based on analysis of microsatellite data. Conserv Biol 20:1768–1779CrossRefPubMedGoogle Scholar
- Wright S (1969) Evolution and the genetics of populations. The theory of gene frequencies, vol 2. University of Chicago Press, ChicagoGoogle Scholar