Diminished Neural Responses to Emotionally Valenced Facial Stimuli: A Potential Biomarker for Unemotional Traits in Early Childhood
Callous-unemotional (CU) traits are characterized by deficits in guilt/empathy, shallow affect, and the callous and manipulative use of others. Individuals showing CU traits have increased risk for behavior problems and reduced responses to displays of distress in others. To explore how deficits in emotion-processing are associated with CU traits, the current study examined the association between callous-unemotionality and a neural index of facial emotion processing, using the event-related potential technique in a group of 3–5 year olds. Children viewed a series of static emotional faces, depicting either fear or happiness, while electroencephalography data were collected. The N170 component, thought to index the neural processes associated with face perception, was examined along with CU traits. Findings suggest that the unemotional dimension of CU traits is associated with diminished emotion-processing responses to fearful faces. Reduced neural responses to facial depictions of fear could be a biomarker for unemotional traits in early childhood.
KeywordsCU traits Unemotional traits Event-related potential Early childhood
This project was supported by a Project Development Team within the ICTSI NIH/NCRR Grant Number TR000006 and the Department of Criminal Justice, Indiana University Bloomington. Caroline Hoyniak is supported by a Graduate Research Fellowship from the National Science Foundation Grant Number 1342962. Dr. Nathalie Fontaine is a Research Scholar, Junior 1, Fonds de recherche du Québec–Santé. We thank Professors Dennis Molfese, Aina Puce and Bennett Bertenthal for their support, and gratefully acknowledge the contribution of the research assistants, families, and children.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 4.Fontaine NM, Rijsdijk FV, McCrory EJ, Viding E (2010) Etiology of different developmental trajectories of callous-unemotional traits. J Am Acad Child Adolesc Psychiatry 49:656–664Google Scholar
- 27.Rossion B, Jacques C (2011) The N170: understanding the time-course of face perception in the human brain. In Luck S, Kappenman E (eds), The Oxford handbook of event-related potential components, Oxford University Press, Oxford, pp 115–142Google Scholar
- 38.Lilienfeld S, Widows M (2005) Psychopathic personality inventory-revised: professional manual. Psychological Assessment Resources, LutzGoogle Scholar
- 41.Hollingshead AB (1975) Four factor index of social status. Unpublished workGoogle Scholar
- 42.Dunn LM, Dunn DM (2007) PPVT-4: Peabody picture vocabulary test. Pearson Assessments, MinneapolisGoogle Scholar
- 49.Frick PJ (2004) The inventory of callous-unemotional traits. Unpublished rating scale. University of New OrleansGoogle Scholar
- 51.Dien J, Frishkoff GA (2005) Introduction to principal components analysis of event-related potentials. In: Handy TC (ed) Event related potentials: a methods handbook. MIT Press, Cambridge, pp 189–207Google Scholar
- 56.R Core Team (2012) R: a language and environment for statistical computing. R Core Team, ViennaGoogle Scholar
- 57.White SF, Williams WC, Brislin SJ, Sinclair S, Blair KS, Fowler KA et al (2012) Reduced activity within the dorsal endogenous orienting of attention network to fearful expressions in youth with disruptive behavior disorders and psychopathic traits. Dev Psychopathol 24:1105–1116CrossRefGoogle Scholar