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Child Psychiatry & Human Development

, Volume 42, Issue 4, pp 424–441 | Cite as

Still Struggling: Characteristics of Youth With OCD Who are Partial Responders to Medication Treatment

  • J. Freeman
  • J. Sapyta
  • A. Garcia
  • D. Fitzgerald
  • M. Khanna
  • M. Choate-Summers
  • P. Moore
  • A. Chrisman
  • N. Haff
  • A. Naeem
  • J. March
  • M. Franklin
Original Article

Abstract

The primary aim of this paper is to examine the characteristics of a large sample of youth with OCD who are partial responders (i.e., still have clinically significant symptoms) to serotonin reuptake inhibitor (SRI) medication. The sample will be described with regard to: demographics, treatment history, OCD symptoms/severity, family history and parental psychopathology, comorbidity, and global and family functioning. The sample includes 124 youth with OCD ranging in age from 7 to 17 with a primary diagnosis of OCD and a partial response to an SRI medication. The youth are a predominantly older (age 12 and over), Caucasian, middle to upper income group who had received significant past treatment. Key findings include moderate to severe OCD symptoms, high ratings of global impairment, and significant comorbidity, despite partial response to an adequate medication trial. Considerations regarding generalizability of the sample and limitations of the study are discussed.

Keywords

Pediatric obsessive compulsive disorder (OCD) Serotonin reuptake inhibitor (SRI) Partial responder Phenomenology 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • J. Freeman
    • 1
    • 2
    • 3
  • J. Sapyta
    • 4
  • A. Garcia
    • 1
  • D. Fitzgerald
    • 4
  • M. Khanna
    • 5
  • M. Choate-Summers
    • 1
  • P. Moore
    • 6
  • A. Chrisman
    • 4
  • N. Haff
    • 1
  • A. Naeem
    • 7
  • J. March
    • 4
  • M. Franklin
    • 5
  1. 1.Department of Psychiatry and Human BehaviorAlpert Medical School of Brown UniversityProvidenceUSA
  2. 2.Division of Child and Adolescent Psychiatry, Rhode Island Hospital and Bradley/Hasbro Children’s Research CenterProvidenceUSA
  3. 3.Pediatric Anxiety Research Clinic, Rhode Island Hospital and Bradley/Hasbro Children’s Research CenterProvidenceUSA
  4. 4.Duke University School of MedicineDurhamUSA
  5. 5.University of Pennsylvania School of MedicinePhiladelphiaUSA
  6. 6.University of Massachusetts Medical SchoolWorcesterUSA
  7. 7.The Children’s Hospital of PhiladelphiaPhiladelphiaUSA

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