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Cellulose

, Volume 27, Issue 1, pp 335–345 | Cite as

Regenerated cellulose-based composite membranes as adsorbent for protein adsorption

  • Qi Zhou
  • Yuping Bao
  • Hao Zhang
  • Qian Luan
  • Hu TangEmail author
  • Xiuting LiEmail author
Original Research
  • 141 Downloads

Abstract

The development of protein adsorbents with high adsorption performance has attracted great attention due to the important role of these adsorbents in protein separation and purification. Herein, cellulose-based composite membranes were prepared through a combination of cellulose fiber (CF) and 2,2,6,6-tetramethylpiperidine-1-oxyl oxidized cellulose nanofiber (CNF) in alkaline/urea aqueous solution and regeneration from a tape casting method. Taking advantage of the functional carboxyl groups in CNF, the obtained cellulose-based composite membranes display a good protein adsorption property, with a capacity of 241.6 mg g−1, by using bovine serum albumin as a model protein. Meanwhile, the adsorption performance of cellulose-based composite membranes can be optimized by regulating the blending ratios of CNF and CF, buffer pH, initial protein concentrations and temperature, and the mechanical property of cellulose-based composite membranes can be adjusted by changing the ratio of CNF and CF. These effective and economic membranes may act as promising candidates for protein adsorption in protein separation and purification fields.

Keywords

Cellulose nanofiber Cellulose fiber Membrane Protein adsorption 

Notes

Acknowledgments

This work was supported by the Open Project from Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU) (No. 20182013).

Supplementary material

10570_2019_2761_MOESM1_ESM.docx (232 kb)
Supplementary material 1 (DOCX 231 kb)

References

  1. Abedini R (2011) A novel cellulose acetate (CA) membrane using TiO2 nanoparticles: preparation, characterization and permeation study. Desalination 277:40–45Google Scholar
  2. Bhatt N, Gupta PK, Naithani S (2011) Hydroxypropyl cellulose from α-cellulose isolated from Lantana camara with respect to DS and rheological behavior. Carbohydr Polym 86:1519–1524Google Scholar
  3. Castro GR, Jingsong C, Bruce P, Kaplan DL (2009) Emulsan-alginate beads for protein adsorption. J Biomater Sci Polym Ed 20:411–426PubMedGoogle Scholar
  4. Chang F, Yamabuki K, Onimura K, Oishi T (2008) Modification of cellulose by using atom transfer radical polymerization and ring-opening polymerization. Polym J 40:1170–1179Google Scholar
  5. Dinand E, Vignon M, Chanzy H, Heux L (2002) Mercerization of primary wall cellulose and its implication for the conversion of cellulose I → cellulose II. Cellulose 9:7–18Google Scholar
  6. Doulabi AH, Mirzadeh H, Imani M, Samadi N (2013) Chitosan/polyethylene glycol fumarate blend film: physical and antibacterial properties. Carbohydr Polym 92:48–56Google Scholar
  7. Duan J, He X, Zhang L (2015) Magnetic cellulose–TiO2 nanocomposite microspheres for highly selective enrichment of phosphopeptides. Chem Commun 51:338–341Google Scholar
  8. Dubey V, Pandey LK, Saxena C (2005) Pervaporative separation of ethanol/water azeotrope using a novel chitosan-impregnated bacterial cellulose membrane and chitosan-poly(vinyl alcohol) blends. J Membr Sci 251:131–136Google Scholar
  9. Foo KY, Hameed BH (2010) Insights into the modeling of adsorption isotherm systems. Chem Eng J 156:2–10Google Scholar
  10. Fu Q, Wang X, Si Y, Liu L, Yu J, Ding B (2016) Scalable fabrication of electrospun nanofibrous membranes functionalized with citric acid for high-performance protein adsorption. ACS Appl Mater Interfaces 8:11819–11829PubMedGoogle Scholar
  11. Fu LH, Qi C, Liu YJ, Cao WT, Ma MG (2018) Sonochemical synthesis of cellulose/hydroxyapatite nanocomposites and their application in protein adsorption. Sci Rep 8:8292–8303PubMedPubMedCentralGoogle Scholar
  12. Handschuh-Wang S, Wang T, Druzhinin SI, Wesner D, Jiang X, Schönherr H (2016) Detailed study of BSA adsorption on micro- and nanocrystalline diamond/β-SiC composite gradient films by time-resolved fluorescence microscopy. Langmuir 33:802–813Google Scholar
  13. Hao W, Chao T, Tian H, Li Y, Wang J (2018) Fabrication of functional magnetic cellulose nanocomposite membranes for controlled adsorption of protein. Cellulose 25:2977–2986Google Scholar
  14. Hazarika P, Behrendt JM, Petersson L, Wingren C, Turner ML (2014) Photopatterning of self assembled monolayers on oxide surfaces for the selective attachment of biomolecules. Biosens Bioelectron 53:82–89PubMedGoogle Scholar
  15. Hlady V, Buijs J, Jennissen HP (1999) Methods for studying protein adsorption. Methods Enzymol 309:402–429PubMedPubMedCentralGoogle Scholar
  16. Hu T, Chang C, Zhang L (2011) Efficient adsorption of Hg2 + ions on chitin/cellulose composite membranes prepared via environmentally friendly pathway. Chem Eng J 173:689–697Google Scholar
  17. Hubbe MA, Beck KR, O’Neal WG, Sharma YC (2012) Cellulosic substrates for removal of pollutants from aqueous systems: a review. 2. Dyes. Bioresources 7:2592–2687Google Scholar
  18. Iriarte-Velasco U, Chimeno-AlaníS N, GonzáLez-Marcos MP, Álvarez-Uriarte JI (2011) Relationship between thermodynamic data and adsorption/desorption performance of acid and basic dyes onto activated carbons. J Chem Eng Data 56:2100–2109Google Scholar
  19. Jie C, Lina Z (2006) Unique gelation behavior of cellulose in NaOH/urea aqueous solution. Biomacromol 7:183–189Google Scholar
  20. Juang LC, Wang CC, Lee CK (2006) Adsorption of basic dyes onto MCM-41. Chemosphere 64:1920–1928PubMedGoogle Scholar
  21. Kamide K, Okajima K, Kowsaka K, Matsui T, Nomura S, Hikichi K (1985) Effect of the distribution of substitution of the sodium salt of carboxymethylcellulose on its absorbency toward aqueous liquid. Polym J 17:909–918Google Scholar
  22. Khattri SD, Singh MK (2009) Removal of malachite green from dye wastewater using neem sawdust by adsorption. J Hazard Mater 167:1089–1094PubMedGoogle Scholar
  23. Luan Q et al (2017) Cellulose-based composite macrogels from cellulose fiber and cellulose nanofiber as intestine delivery vehicles for probiotics. J Agric Food Chem 66:339–345PubMedGoogle Scholar
  24. Luo X, Liu S, Zhou J, Zhang L (2009) In situ synthesis of Fe3O4/cellulose microspheres with magnetic-induced protein delivery. J Mater Chem 19:3538–3545Google Scholar
  25. Madaeni SS, Heidary F (2011) Improving separation capability of regenerated cellulose ultrafiltration membrane by surface modification. Appl Surf Sci 257:4870–4876Google Scholar
  26. Marek K (2014) The pH dependent surface charging and points of zero charge. VI. Update. J Colloid Interface Sci 426:209–212Google Scholar
  27. Meng H, Chang C, Na P, Zhang L (2012) Structure and properties of hydroxyapatite/cellulose nanocomposite films. Carbohydr Polym 87:2512–2518Google Scholar
  28. Montanari S, Roumani M, Laurent Heux A, Vignon MR (2008) Topochemistry of carboxylated cellulose nanocrystals resulting from TEMPO-mediated oxidation. Macromolecules 38:1665–1671Google Scholar
  29. Pelton R (2009) Bioactive paper provides a low-cost platform for diagnostics. TrAC Trends Anal Chem 28:925–942Google Scholar
  30. Richter AG, Ivan K (2013) Using in situ X-ray reflectivity to study protein adsorption on hydrophilic and hydrophobic surfaces: benefits and limitations. Langmuir 29:5167–5180PubMedGoogle Scholar
  31. Sadir S, Prabhakaran MP, Wicaksono DHB, Ramakrishna S (2014) Fiber based enzyme-linked immunosorbent assay for C-reactive protein. Sensors Actuators B Chem 205:50–60Google Scholar
  32. Sahadevan R, Crandall C, Schneiderman S, Menkhaus TJ (2018) Cellulose-graft-polyethyleneamidoamine anion-exchange nanofiber membranes for simultaneous protein adsorption and virus filtration. ACS Appl Nano Mater 1:3321–3330Google Scholar
  33. Sang YO et al (2005) Crystalline structure analysis of cellulose treated with sodium hydroxide and carbon dioxide by means of X-ray diffraction and FTIR spectroscopy. Carbohydr Res 340:2376–2391Google Scholar
  34. Sun XF, Wang SG, Liu XW, Gong WX, Bao N, Gao BY, Zhang HY (2008) Biosorption of Malachite Green from aqueous solutions onto aerobic granules: kinetic and equilibrium studies. Biores Technol 99:3475–3483Google Scholar
  35. Tailor R, Shah BA, Shah AV (2012) Sorptive removal of phenol by zeolitic bagasse fly ash: equilibrium, kinetics, and column studies. J Chem Eng Data 57:1437–1448Google Scholar
  36. Tsuguyuki S, Satoshi K, Yoshiharu N, Akira I (2007) Cellulose nanofibers prepared by TEMPO-mediated oxidation of native cellulose. Biomacromol 8:2485–2491Google Scholar
  37. Udoetok IA, Dimmick RM, Wilson LD, Headley JV (2016) Adsorption properties of cross-linked cellulose-epichlorohydrin polymers in aqueous solution. Carbohydr Polym 136:329–340PubMedGoogle Scholar
  38. Yang F, Wang J, Hou J, Guo H, Liu C (2013) Bone regeneration using cell-mediated responsive degradable PEG-based scaffolds incorporating with rhBMP-2. Biomaterials 34:1514–1528PubMedGoogle Scholar
  39. Zhang H et al (2017) Cellulose anionic hydrogels based on cellulose nanofibers as natural stimulants for seed germination and seedling growth. J Agric Food Chem 65:3785–3791PubMedGoogle Scholar
  40. Zhang H et al (2018) A pH-responsive gel macrosphere based on sodium alginate and cellulose nanofiber for potential intestinal delivery of probiotics. ACS Sustain Chem Eng 6:13924–13931Google Scholar
  41. Zhao ZP, Wang Z, Wang SC (2003) Formation, charged characteristic and BSA adsorption behavior of carboxymethyl chitosan/PES composite MF membrane. J Membr Sci 217:151–158Google Scholar
  42. Zhu B, Nan M, Wu D, Sun Y, Li W (2011) Synergistic extraction and selective removal of Cu2+ from aqueous solution using magnetic nanoparticles coated with mixtures of sodium oleate and saponified 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester. Ind Eng Chem Res 50:11698–11705Google Scholar

Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Beijing Advanced Innovation Center for Food Nutrition and Human HealthBeijing Technology and Business UniversityBeijingChina
  2. 2.Key Laboratory of Oilseeds Processing, Ministry of Agriculture, Hubei Key Laboratory of Lipid Chemistry and Nutrition, Oil Crops and Lipids Process Technology National and Local Joint Engineering LaboratoryOil Crops Research Institute, Chinese Academy of Agricultural SciencesWuhanChina

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