Advertisement

Cellulose

pp 1–21 | Cite as

Microwave assisted in situ synthesis of gum Salai guggal based silver nanocomposites- investigation of anti-bacterial properties

  • Amit Kumar SharmaEmail author
  • Balbir Singh Kaith
  • Bhuvanesh Gupta
  • Uma Shanker
  • Satya Pal Lochab
Original Paper
  • 39 Downloads

Abstract

This paper describes the fabrication of silver nanocomposites based on semi interpenetrating network (semi-IPN) and interpenetrating network (IPN) matrices and their antibacterial activity. The semi-IPN and IPN matrices were prepared under microwave radiation using polyacrylic acid and polyacrylamide chains to graft copolymerize the polysaccharide fraction of gum Salai guggal. After optimizing the reaction parameters with respect to maximum water absorption capacity, the synthesized semi-IPN and IPN were found to show 1350% and 483% swelling percentage, respectively. The semi-IPN and IPN matrices were converted into their respective silver nanocomposites through swelling- shrinking process via the immersion of super absorbents in AgNO3 aqueous solution and irradiation of samples with gamma rays. FTIR, SEM–EDS, HR-TEM, XRD and UV–Vis studies confirmed the formation of silver nanocomposites. The 3-D crosslinked polymeric structures of the matrix phase regulate the particle size between 8.19–28.83 and 1.27–4.14 nm for the silver nanoparticles derived through semi-IPN nanocomposite (Sg-cl-polyAAm-MW-Ag0) and IPN nanocomposite (Sg-cl-polyAAm-IPN-AA-MW-Ag0) matrix templates, respectively. The silver nanocomposites were evaluated for antibacterial activity against Pseudomonas aeruginosa, Bacillus cereus, Staphylococcus aureus and Escherichia coli bacteria. It was found that all the samples have potential activity against these bacteria and thus can be used for biomedical applications like scaffolds to inhibit bacterial infections.

Graphical abstract

Keywords

Nanocomposite Superabsorbent Crosslinked 

Notes

Acknowledgments

One of the authors is extremely thankful to Inter University Accelerator Centre (IUAC) New-Delhi, India, for providing financial assistance and gamma radiation facility for carrying out his research work. The author is also grateful to instrumentation centre, IIT Roorkee, for the characterization of samples, DST-FIST New Delhi for acquiring the UV–visible and FTIR spectrophotometers at NIT Jalandhar and Department of Biotechnology, NIT Jalandhar, India, for the antimicrobial studies.

References

  1. Aihara N, Torigoe K, Esumi K (1998) Preparation and characterization of gold and silver nanoparticles in layered laponite suspensions. Langmuir 14:4945–4949.  https://doi.org/10.1021/la980370p CrossRefGoogle Scholar
  2. Baek K, Liang J, Lim WT et al (2015) In situ assembly of antifouling/bacterial silver nanoparticle-hydrogel composites with controlled particle release and matrix softening. ACS Appl Mater Interfaces 7:15359–15367.  https://doi.org/10.1021/acsami.5b03313 CrossRefPubMedGoogle Scholar
  3. Bajpai SK, Mohan YM, Bajpai M et al (2007) Synthesis of polymer stabilized silver and gold nanostructures. J Nanosci Nanotechnol 7:2994–3010.  https://doi.org/10.1166/Jnn.2007.911 CrossRefPubMedGoogle Scholar
  4. Banerjee SL, Khamrai M, Kundu PP, Singha NK (2016) Synthesis of a self-healable and pH responsive hydrogel based on an ionic polymer/clay nanocomposite. RSC Adv 6:81654–81665.  https://doi.org/10.1039/c6ra01074a CrossRefGoogle Scholar
  5. Beveridge TJ (1999) Structures of gram-negative cell walls and their derived membrane vesicles. J Bacteriol 181:4725–4733PubMedPubMedCentralGoogle Scholar
  6. Bin Ahmad M, Lim JJ, Shameli K et al (2011) Synthesis of silver nanoparticles in chitosan, gelatin and chitosan/gelatin bionanocomposites by a chemical reducing agent and their characterization. Molecules 16:7237–7248.  https://doi.org/10.3390/molecules16097237 CrossRefPubMedGoogle Scholar
  7. Carlson C, Hussein SM, Schrand AM et al (2008) Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J Phys Chem B 112:13608–13619.  https://doi.org/10.1021/jp712087m CrossRefPubMedGoogle Scholar
  8. Dibrov P, Dzioba J, Gosink KK, Häse CC (2002) Chemiosmotic mechanism of antimicrobial activity of Ag+ in Vibrio cholerae. Antimicrob Agents Chemother 46:2668–2670.  https://doi.org/10.1128/AAC.46.8.2668-2670.2002 CrossRefPubMedPubMedCentralGoogle Scholar
  9. El-Batal AI, Hashem AAM, Abdelbaky NM (2013) Gamma radiation mediated green synthesis of gold nanoparticles using fermented soybean-garlic aqueous extract and their antimicrobial activity. Springerplus.  https://doi.org/10.1186/2193-1801-2-129 CrossRefPubMedPubMedCentralGoogle Scholar
  10. Esumi K, Suzuki A, Yamahira A, Torigoe K (2000) Role of poly(amidoamine) dendrimers for preparing nanoparticles of gold, platinum, and silver. Langmuir 16:2604–2608.  https://doi.org/10.1021/la991291w CrossRefGoogle Scholar
  11. Esumi K, Isono R, Yoshimura T (2004) Preparation of PAMAM- and PPI-metal (slver, platinum, and palladium) nanocomposites and their catalytic activities for reduction of 4-nitrophenol. Langmuir 20:237–243.  https://doi.org/10.1021/la035440t CrossRefPubMedGoogle Scholar
  12. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO (2000) A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res 52:662–668CrossRefGoogle Scholar
  13. Gajendiran M, Gopi V, Elangovan V et al (2013) Isoniazid loaded core shell nanoparticles derived from PLGA-PEG-PLGA tri-block copolymers: in vitro and in vivo drug release. Colloids Surf B Biointerfaces 104:107–115.  https://doi.org/10.1016/j.colsurfb.2012.12.008 CrossRefPubMedGoogle Scholar
  14. Gálvez N, Fernández B, Sánchez P et al (2009) Magnetic-fluorescent Langmuir-Blodgett films of fluorophore-labeled ferritin nanoparticles. Solid State Sci 11:754–759.  https://doi.org/10.1016/j.solidstatesciences.2008.04.026 CrossRefGoogle Scholar
  15. Ghavaminejad A, Park CH, Kim CS (2016) In situ synthesis of antimicrobial silver nanoparticles within antifouling zwitterionic hydrogels by catecholic redox chemistry for wound healing application. Biomacromol 17:1213–1223.  https://doi.org/10.1021/acs.biomac.6b00039 CrossRefGoogle Scholar
  16. Goy RC, Morais STB, Assis OBG (2016) Evaluation of the antimicrobial activity of chitosan and its quaternized derivative on E. Coli and S. aureus growth. Braz J pharmacogn 26:122–127.  https://doi.org/10.1016/j.bjp.2015.09.010 CrossRefGoogle Scholar
  17. Gratzl G, Walkner S, Hild S et al (2015) Mechanistic approaches on the antibacterial activity of poly(acrylic acid) copolymers. Colloids Surf B Biointerfaces 126:98–105.  https://doi.org/10.1016/j.colsurfb.2014.12.016 CrossRefPubMedGoogle Scholar
  18. Hoffman AS (2012) Hydrogels for biomedical applications. Adv Drug Deliv Rev 64:18–23CrossRefGoogle Scholar
  19. Hussain ISA, Jaisankar V (2017) An eco-friendly synthesis, characterization and antibacterial applications of novel almond gum – poly(acrylamide) based hydrogel silver nanocomposite. Polym Test 62:154–161.  https://doi.org/10.1016/j.polymertesting.2017.06.021 CrossRefGoogle Scholar
  20. Inomata H, Goto S, Saito S (1990) Phase transition of n-substituted acrylamide gels. Macromolecules 23:4887–4888.  https://doi.org/10.1021/ma00224a023 CrossRefGoogle Scholar
  21. Işιk B (2004) Swelling behavior and determination of diffusion characteristics of acrylamide—acrylic acid hydrogels. J Appl Polym Sci 91:1289–1293.  https://doi.org/10.1002/app.13270 CrossRefGoogle Scholar
  22. Jovanović Ž, Radosavljević A, Kačarević-Popović Z et al (2013) Bioreactor validation and biocompatibility of Ag/poly(N-vinyl-2-pyrrolidone) hydrogel nanocomposites. Colloids Surf B Biointerfaces 105:230–235.  https://doi.org/10.1016/j.colsurfb.2012.12.055 CrossRefPubMedGoogle Scholar
  23. Kabiri K, Omidian H, Zohuriaan-Mehr MJ, Doroudiani S (2011) Superabsorbent hydrogel composites and nanocomposites: a review. Polym Compost 32:277–289.  https://doi.org/10.1002/pc.21046 CrossRefGoogle Scholar
  24. Kaith BS, Sukriti Sharma J et al (2016) Microwave-assisted green synthesis of hybrid nanocomposite: removal of Malachite green from waste water (English Ed). Iran Polym J 25:787–797.  https://doi.org/10.1007/s13726-016-0467-z CrossRefGoogle Scholar
  25. Kaith BS, Jindal R et al (2017) Biodegradable-stimuli sensitive xanthan gum based hydrogel: evaluation of antibacterial activity and controlled agro-chemical release. React Funct Polym 120:1–13.  https://doi.org/10.1016/j.reactfunctpolym.2017.08.012 CrossRefGoogle Scholar
  26. Kaur I, Khanna ND (2011) Synthesis and characterization of dextrin-grafted polypropylene. J Appl Polym Sci 119:1090–1101.  https://doi.org/10.1002/app.32663 CrossRefGoogle Scholar
  27. Khare AR, Peppas NA (1995) Swelling/deswelling of anionic copolymer gels. Biomaterials 16:559–567.  https://doi.org/10.1016/0142-9612(95)91130-Q CrossRefPubMedGoogle Scholar
  28. Li Y, Tan Y, Xu K et al (2015) In situ crosslinkable hydrogels formed from modified starch and O-carboxymethyl chitosan. RSC Adv 5:30303–30309.  https://doi.org/10.1039/c4ra14984j CrossRefGoogle Scholar
  29. Marignier JL, Belloni J, Delcourt MO, Chevalier JP (1985) Microaggregates of non-noble metals and bimetallic alloys prepared by radiation-induced reduction. Nature 317:344–345.  https://doi.org/10.1038/317344a0 CrossRefGoogle Scholar
  30. Mei L, Lu Z, Zhang X et al (2014) Polymer-Ag nanocomposites with enhanced antimicrobial activity against bacterial infection. ACS Appl Mater Interfaces 6:15813–15821.  https://doi.org/10.1021/am502886m CrossRefPubMedGoogle Scholar
  31. Mendis E, Rajapakse N, Byun HG, Kim SK (2005) Investigation of jumbo squid (Dosidicus gigas) skin gelatin peptides for their in vitro antioxidant effects. Life Sci 77:2166–2178.  https://doi.org/10.1016/j.lfs.2005.03.016 CrossRefPubMedGoogle Scholar
  32. Mittal H, Kaith BS, Jindal R et al (2015) A comparative study on the effect of different reaction conditions on graft co-polymerization, swelling, and thermal properties of Gum ghatti-based hydrogels. J Therm Anal Calorim 119:131–144.  https://doi.org/10.1007/s10973-014-4140-5 CrossRefGoogle Scholar
  33. Morones JR, Elechiguerra JL, Camacho A, Ramirez JT (2005) The bactericidal effect of silver nanoparticles. Nanotechnology.  https://doi.org/10.1088/0957-4484/16/10/059 CrossRefPubMedGoogle Scholar
  34. Mu Q, Jiang G, Chen L et al (2014) Chemical basis of interactions between engineered nanoparticles and biological systems. Chem Rev 114:7740–7781.  https://doi.org/10.1021/cr400295a CrossRefPubMedPubMedCentralGoogle Scholar
  35. Munarin F, Petrini P, Farè S, Tanzi MC (2010) Structural properties of polysaccharide-based microcapsules for soft tissue regeneration. J Mater Sci Mater Med 21:365–375.  https://doi.org/10.1007/s10856-009-3860-8 CrossRefPubMedGoogle Scholar
  36. Murthy PSK, Mohan YM, Sreeramulu J, Raju KM (2006) Semi-IPNs of starch and poly(acrylamide-co-sodium methacrylate): preparation, swelling and diffusion characteristics evaluation. React Funct Polym 66:1482–1493.  https://doi.org/10.1016/j.reactfunctpolym.2006.04.010 CrossRefGoogle Scholar
  37. Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(80):622–627.  https://doi.org/10.1126/science.1114397 CrossRefPubMedGoogle Scholar
  38. Palmer D, Levina M, Douroumis D et al (2013) Mechanism of synergistic interactions and its influence on drug release from extended release matrices manufactured using binary mixtures of polyethylene oxide and sodium carboxymethylcellulose. Colloids Surf B Biointerfaces 104:174–180.  https://doi.org/10.1016/j.colsurfb.2012.11.025 CrossRefPubMedGoogle Scholar
  39. Pandey M, Mohd Amin MCI, Ahmad N, Abeer MM (2013) Rapid synthesis of superabsorbent smart-swelling bacterial cellulose/acrylamide-based hydrogels for drug delivery. Int J Polym Sci.  https://doi.org/10.1155/2013/905471 CrossRefGoogle Scholar
  40. Park K (1997) Controlled drug delivery: challenges and strategies. ACS Prof Ref B xvii:629Google Scholar
  41. Peppas NA, Bures P, Leobandung W, Ichikawa H (2000) Hydrogels in pharmaceutical formulations. Eur J Pharm Biopharm 50:27–46.  https://doi.org/10.1016/S0939-6411(00)00090-4 CrossRefPubMedGoogle Scholar
  42. Perez-Moral N, Gonzalez MC, Parker R (2013) Preparation of iron-loaded alginate gel beads and their release characteristics under simulated gastrointestinal conditions. Food Hydrocoll.  https://doi.org/10.1016/j.foodhyd.2012.09.015 CrossRefGoogle Scholar
  43. Pinto RJB, Marques PAAP, Neto CP et al (2009) Antibacterial activity of nanocomposites of silver and bacterial or vegetable cellulosic fibers. Acta Biomater 5:2279–2289.  https://doi.org/10.1016/j.actbio.2009.02.003 CrossRefPubMedGoogle Scholar
  44. Pourjavadi A, Barzegar S, Mahdavinia GR (2006) MBA-crosslinked Na-Alg/CMC as a smart full-polysaccharide superabsorbent hydrogels. Carbohydr Polym 66:386–395.  https://doi.org/10.1016/j.carbpol.2006.03.013 CrossRefGoogle Scholar
  45. Rodríguez-León E, Iñiguez-Palomares R, Navarro RE et al (2013) Synthesis of silver nanoparticles using reducing agents obtained from natural sources (Rumex hymenosepalus extracts). Nanoscale Res Lett 8:1–9.  https://doi.org/10.1186/1556-276X-8-318 CrossRefGoogle Scholar
  46. Rojas JV, Castano CH (2012) Production of palladium nanoparticles supported on multiwalled carbon nanotubes by gamma irradiation. Radiat Phys Chem 81:16–21.  https://doi.org/10.1016/j.radphyschem.2011.08.010 CrossRefGoogle Scholar
  47. Russell AD, Hugo WB (1994) Antimicrobial activity and action of silver. Prog Med Chem 31:351–370.  https://doi.org/10.1016/S0079-6468(08)70024-9 CrossRefPubMedGoogle Scholar
  48. Scognamillo S, Alzari V, Nuvoli D, Mariani A (2010) Thermoresponsive super waterabsorbent hydrogels prepared by frontal polymerization. J Polym Sci Part A Polym Chem 48:2486–2490CrossRefGoogle Scholar
  49. Shrivastava S, Bera T, Roy A et al (2007) Characterization of enhanced antibacterial effects of novel silver nanoparticles. Nanotechnology 18:1–9.  https://doi.org/10.1088/0957-4484/18/22/225103 CrossRefGoogle Scholar
  50. Singhal R, Tomar RS, Nagpal AK (2009) Effect of cross-linker and initiator concentration on the swelling behaviour and network parameters of superabsorbent hydrogels based on acrylamide and acrylic acid. Int J Plast Technol 13:22–37CrossRefGoogle Scholar
  51. Sukriti, Kaith BS, Jindal R (2017) Ag+9 swift heavy ion irradiation: augmented removal of auramine-O dye and bactericidal activity. Int J Theor Appl Sci 9:11–24Google Scholar
  52. Tanan W, Saengsuwan S (2014) Microwave assisted synthesis of poly (acrylamide-co-2-hydroxyethyl methacrylate)/poly(vinyl alcohol) semi-IPN hydrogel. Energy Proc 56:386–393.  https://doi.org/10.1016/j.egypro.2014.07.171 CrossRefGoogle Scholar
  53. Travan A, Pelillo C, Donati I et al (2009) Non-cytotoxic silver nanoparticle-polysaccharide nanocomposites with antimicrobial activity. Biomacromol 10:1429–1435.  https://doi.org/10.1021/bm900039x CrossRefGoogle Scholar
  54. Tsuruta T, Hayashi T, Kataoka K, Ishihara K, Kamura Y (1993) A review of: “Biomedical applications of polymeric materials”. J Disper Sci Technol 14:718.  https://doi.org/10.1080/01932699308943444 CrossRefGoogle Scholar
  55. Veerasamy R, Xin TZ, Gunasagaran S et al (2011) Biosynthesis of silver nanoparticles using mangosteen leaf extract and evaluation of their antimicrobial activities. J Saudi Chem Soc.  https://doi.org/10.1016/j.jscs.2010.06.004 CrossRefGoogle Scholar
  56. Vimala K, Sivudu KS, Murali Mohan Y et al (2009) Controlled silver nanoparticles synthesis in semi-hydrogel networks of poly(acrylamide) and carbohydrates: a rational methodology for antibacterial application. Carbohydr Polym 75:463–471.  https://doi.org/10.1016/j.carbpol.2008.08.009 CrossRefGoogle Scholar
  57. Wang L, Xu Y (2006) Preparation and characterization of graft copolymerization of ethyl acrylate onto hydroxypropyl methylcellulose in aqueous medium. Cellulose.  https://doi.org/10.1007/s10570-005-9043-y CrossRefGoogle Scholar
  58. Wei L, Lu J, Xu H, Patel A, Chen Z, Chen G (2014) Silver nanoparticles: synthesis, properties, and therapeutic applications. Drug Discov Today 20:595–601.  https://doi.org/10.1016/j.drudis.2014.11.014 CrossRefPubMedPubMedCentralGoogle Scholar
  59. Wu W, He Q, Jiang C (2008) Magnetic iron oxide nanoparticles: Synthesis and surface functionalization strategies. Nanoscale Res Lett.  https://doi.org/10.1007/s11671-008-9174-9 CrossRefPubMedPubMedCentralGoogle Scholar
  60. Xu S, Deng L, Zhang J et al (2016) Composites of electrospun-fibers and hydrogels: a potential solution to current challenges in biological and biomedical field. J Biomed Mater Res Part B Appl Biomater 104:640–656.  https://doi.org/10.1002/jbm.b.33420 CrossRefPubMedGoogle Scholar
  61. Yallapu MM, Othman SF, Curtis ET, Gupta BK, Jaggi MCS (2011) Multi-functional magnetic nanoparticles for magnetic resonance imaging and cancer therapy. Biomaterials 32(7):1890–1905CrossRefGoogle Scholar
  62. Zhou Y, Kong Y, Kundu S et al (2012) Antibacterial activities of gold and silver nanoparticles against Escherichia coli and Bacillus Calmette-Guérin. J Nanobiotechnol.  https://doi.org/10.1186/1477-3155-10-19 CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Amit Kumar Sharma
    • 1
    Email author
  • Balbir Singh Kaith
    • 1
  • Bhuvanesh Gupta
    • 2
  • Uma Shanker
    • 1
  • Satya Pal Lochab
    • 3
  1. 1.Department of ChemistryDr B R Ambedkar National Institute of TechnologyJalandharIndia
  2. 2.Department of Textile TechnologyIndian Institute of TechnologyNew DelhiIndia
  3. 3.Inter University Accelerator CentreNew DelhiIndia

Personalised recommendations