Determination of absorption and structural properties of cellulose-based hydrogel via ultrasonic pulse-echo time-of-flight approach
Biodegradable cellulose-based hydrogels are attracting increasing interest in the academic and industrial fields thanks to their high swelling capacity and reproducibility, which allow many novel applications. These properties are enabled by amplification effect of their sensitiveness on a molecular level, translated into macroscopic effects such as a change in swelling degree. The monitoring of the hydrogel state is a crucial step for understanding the response of the hydrogel to external environment. Accordingly, the major aim of this study is to exploit ultrasound to characterize the swelling and degradation of cellulose-based hydrogel with different blend of molecular weight and degree of substitutions. The ultrasonic sensor used herein relies on the determination of a Pulse-echo time of flight. This technique provides dimensional information, thanks to its capability of monitoring the thickness of the swollen/unswollen hydrogel during sorption mechanism. Furthermore, by combining these data with a rheological characterization, the degree of crosslink and its modification during multiple swelling/deswelling cycles (due to ion strength variation) has been monitored. This technique could be an effective, alternative, fast and non-destructive method for real-time hydrogel characterization.
KeywordsCellulose-based hydrogel Ultrasound Time-of-flight Pulse-echo
Compliance with ethical standards
Conflict of interest
The authors declare no competing financial interests.
- Angrisani L et al (2009) Ultrasonic-based distance measurement through discrete extended Kalman filter. Kalman filter recent advances and applications. InTechGoogle Scholar
- Brannon-Peppas L, Peppas N (1990) The equilibrium swelling behavior of porous and non-porous hydrogels. Studies in polymer science. Elsevier 8:67–102Google Scholar
- Buchholz F, Polymers IS (1994) Science and technology. In: Buchholz FL, Peppas NA (eds) ACS symposium seriesGoogle Scholar
- Flory PJ (1953) Principles of polymer chemistry. Cornell University Press, IthacaGoogle Scholar
- Peppas NA (1987) Hydrogels in medicine and pharmacy: properties and applications. CRC PressI Llc, Boca RatonGoogle Scholar
- Ramuhalli P et al (2002) Multichannel signal processing methods for ultrasonic nondestructive evaluation. In: Sensor array and multichannel signal processing workshop proceedings, 2002, IEEEGoogle Scholar
- Sabatini AM, et al (1995) A low-cost, composite sensor array combining ultrasonic and infrared proximity sensors. In: Proceedings. 1995 IEEE/RSJ international conference on intelligent robots and systems 95.’human robot interaction and cooperative robots. IEEEGoogle Scholar
- Zandraa O et al (2011) Viscoelastic properties and morphology of mumio‐based medicated hydrogels. In: AIP conference proceedings, AIPGoogle Scholar