In situ polymerization and characterization of elastomeric polyurethane-cellulose nanocrystal nanocomposites. Cell response evaluation
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Polyurethane/Cellulose nanocrystal (CNC) nanocomposites have been prepared by means of in situ polymerization using CNCs as precursors of polyurethane chains. Thermal, mechanical and morphological characterization has been analyzed to study the effect of CNC on the micro/nanostructure, which consisted of individualized nanocellulose crystallites covalently bonded to hard and soft segments of polyurethane. The incorporation of low CNC content led to a tough material whereas higher amount of CNC provoked an increase in soft and hard segments crystallization phenomenon. Moreover, from the viewpoint of polyurethane and polyurethane nanocomposites applications focused on biomedical devices, biocompatibility studies can be considered necessary to evaluate the influence of CNC on the biological behaviour. SEM micrographs obtained from cells seeded on top of the materials showed that L-929 fibroblasts massively colonized the materials surface giving rise to good substrates for cell adhesion and proliferation and useful as potential materials for biomedical applications.
KeywordsCellulose nanocrystals Polyurethane Biocompatibility Atomic force microscopy
This work was supported by the University of the Basque Country (PIFA/01/2006/045 and PES11/13), the Basque Government ‘Saiotek 11-S-PE11UN132′ and ‘Grupos de Investigación Consolidados’ (IT-776-13). We would like to acknowledge General Research Services from the University of the Basque Country (SGIker) for their technical support. This article is dedicated to Prof. Mondragon, who founded the research group “Materiales + Tecnologías” (GMT) in 1988, in special recognition of the contributions to science research.
Conflict of interest
The authors declare no competing financial interest.
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