Cellulose

, Volume 16, Issue 2, pp 309–317 | Cite as

Rendering cellulose fibers antimicrobial using cationic β-cyclodextrin-based polymers included with antibiotics

  • L. Qian
  • Y. Guan
  • Z. Ziaee
  • B. He
  • A. Zheng
  • H. Xiao
Article
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Received:
Accepted:

Abstract

Cationic β-cyclodextrin polymer (CPβCD) and its complexes with butylparaben and triclosan were reported in this paper. 2D NMR confirmed that the host-guest complexes were formed by including antibiotics inside the cavities of CPβCDs, which significantly improved the water solubility of the antibiotics. Results of inhibition zones and shaking flask methods of antimicrobial-modified cellulose fibres showed that both antibiotics/CPβCD complexes had excellent antimicrobial activities when applying on the cellulose fibers whereas triclosan appeared to more effective. Morphology of untreated and treated bacteria revealed by AFM suggested that the antibiotics/CPβCD complexes inhibited bacteria through affecting the metabolism of the bacteria instead of damaging the cell membrane. Due to the strong electrostatic association, CPβCD polymers adsorbed on the surface of cellulose fibres almost completely within the range of dosages investigated.

Keywords

Cationic β-cyclodextrin polymers Antibiotics Cellulose fiber Inclusion complexes Antimicrobial activity AFM 
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Notes

Acknowledgments

The financial supports for this work from SENTINEL NSERC Canada and NSF of Guangdong (Grant no. 06Z002) are gratefully acknowledged.

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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • L. Qian
    • 1
  • Y. Guan
    • 2
  • Z. Ziaee
    • 3
  • B. He
    • 1
  • A. Zheng
    • 2
  • H. Xiao
    • 3
    • 1
  1. 1.State Key Lab of Pulp and Paper EngineeringSouth China University of TechnologyGuangzhouChina
  2. 2.Key Laboratory for Ultrafine Materials of Ministry of Education & School of Materials Sci & EngineeringEast China University of Science & TechnologyShanghaiChina
  3. 3.Department of Chemical EngineeringUniversity of New BrunswickFrederictonCanada

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