, Volume 15, Issue 4, pp 609–618

Preparation of novel antimicrobial-modified starch and its adsorption on cellulose fibers: Part I. Optimization of synthetic conditions and antimicrobial activities



Antimicrobial-modified starch was synthesized by covalently bonding guanidine polymer (PHGH) with potato starch via coupling reaction. Orthogonal tests were applied to optimize the reaction conditions. The coupling efficiency could reach 90.21% at the optimal conditions: temperature, 70 °C; time, 2 h; PHGH/starch, 120 wt.%; GDE/starch, 8 wt.%; pH, 11. PHGH modified starches exhibited high antimicrobial activities against both E. coli and S. aureus. Shaking flask method was more suitable for current non-released modified starches than diffusion method to evaluate the antimicrobial activities. In the presence of 1.0 wt.% PHGH in wood fibers, the growth inhibition reached almost 100%. The AFM results also demonstrated that the antimicrobial mechanism of PHGH was to destroy the membrane of the cells.


Starch Guanidine polymer Antimicrobial activity Orthogonal test AFM 


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  1. 1.Department of Chemical EngineeringUniversity of New BrunswickFrederictonCanada
  2. 2.State Key Lab of Pulp and Paper EngineeringSouth China University of TechnologyGuangzhouChina
  3. 3.School of Materials Science and Engineering, Key Laboratory for Ultrafine Materials of Ministry of EducationEast China University of Science and TechnologyShanghaiChina

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