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Clinical Child and Family Psychology Review

, Volume 22, Issue 4, pp 478–501 | Cite as

Family-Based Psychological Treatment for Obsessive Compulsive Disorder in Children and Adolescents: A Meta-analysis and Systematic Review

  • Chloë A. McGrath
  • Maree J. AbbottEmail author
Article

Abstract

A significant number of children and adolescents with obsessive compulsive disorder (OCD) demonstrate poor response to the current gold standard treatment, cognitive behaviour therapy (CBT) with exposure and response prevention (ERP). Recent findings suggest that family variables affect treatment response highlighting the need for a meta-analytic review of the precise impact of family variables on OCD-related symptoms and processes. The current review and meta-analysis examined the effect of family-based interventions on OCD symptom and family factor outcomes for children and adolescents with OCD. The moderating effects of the degree of parental involvement and number of family factors targeted in treatment were investigated. An extensive literature search identified 37 eligible studies (1727 OCD participants). Large significant pooled mean effect sizes for OCD symptoms and Family Accommodation (FA), respectively, were obtained at posttest (g = 1.56; g = 1.00) and follow-up (g = 1.69; g = 1.98). Moderator analyses indicated that the number of family factors targeted in treatment significantly moderated outcomes on measures of FA (z = 2.21, p = 0.03), but not on Children’s/Yale-Brown Obsessive Compulsive Scale (C/Y-BOCS) outcomes. FA has been significantly correlated with OCD symptom severity and poorer treatment outcomes, and there is data to suggest that FA may mediate OCD symptom outcomes (e.g., Piacentini et al. in J Am Acad Child Adolesc Psychiatry 50:1149–1161, 2011). Findings show that the greater the number of family factors targeted, the greater the reduction in FA at post, highlighting the importance of addressing a range of family factors in child OCD treatment to optimise outcomes.

Keywords

Obsessive compulsive disorder Treatment Child Family Meta-analysis Systematic review 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

References

  1. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington: American Psychiatric Publishing.CrossRefGoogle Scholar
  2. Barrett, P., Farrell, L., Dadds, M., & Boulter, N. (2005). Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: Long-term follow up and predictors of outcome. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 1005–1014.  https://doi.org/10.1097/01.chi.0000172555.26349.94.CrossRefPubMedGoogle Scholar
  3. Barrett, P. M., Farrell, L., Pina, A. A., Peris, T. S., & Piacentini, J. (2008). Evidence-based psychosocial treatments for child and adolescent obsessive-compulsive disorder. Journal of Clinical Child and Adolescent Psychology, 37, 131–155.  https://doi.org/10.1080/15374410701817956.CrossRefPubMedGoogle Scholar
  4. Barrett, P., Healy-Farrell, L., & March, J. S. (2003). Behavioral avoidance test for childhood obsessive-compulsive disorder: A home-based observation. American Journal of Psychotherapy, 57, 80–99.  https://doi.org/10.1176/appi.psychotherapy.2003.57.1.80.CrossRefPubMedGoogle Scholar
  5. Barrett, P., Healy-Farrell, L., & March, J. S. (2004). Cognitive behavioral family treatment of childhood obsessive-compulsive disorder: A controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 46–62.  https://doi.org/10.1097/00004583-200401000-00014.CrossRefPubMedGoogle Scholar
  6. Barrett, P., Shortt, A., & Healy, L. (2002). Do parent and child behaviours differentiate families whose children have obsessive-compulsive disorder from other clinic and non-clinic families? Journal of Child Psychology and Psychiatry, 43, 597–607.  https://doi.org/10.1111/1469-7610.00049.CrossRefPubMedGoogle Scholar
  7. Benazon, N. R., Ager, J., & Rosenberg, D. R. (2002). Cognitive behavior therapy in treatment-naive children and adolescents with obsessive-compulsive disorder: an open trial. Behaviour Research and Therapy, 40, 529–539.  https://doi.org/10.1016/S0005-7967(01)00064-X.CrossRefPubMedGoogle Scholar
  8. Bipeta, R., Yerramilli, S. S. R. R., Pingali, S., Karredla, A. R., & Ali, M. O. (2013). A cross-sectional study of insight and family accommodation in pediatric obsessive- compulsive disorder. Child and Adolescent Psychiatry and Mental Health, 7, 20.  https://doi.org/10.1186/1753-2000-7-20.CrossRefPubMedPubMedCentralGoogle Scholar
  9. Borenstein, M., Hedges, L., Higgins, J., & Rothstein, H. (2005). Comprehensive meta-analysis (Version 2). Englewood: Biostat.Google Scholar
  10. Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009). Introduction to meta-analysis. Chichester: John Wiley and Sons Ltd.CrossRefGoogle Scholar
  11. Brauer, L., Lewin, A. B., & Storch, E. A. (2011). Evidence-based treatment for pediatric obsessive-compulsive disorder. The Israel Journal of Psychiatry and Related Sciences, 48, 280–287.PubMedGoogle Scholar
  12. Calvocoressi, L., Lewis, B., Harris, M., Trufan, S. J., Goodman, W. K., McDougle, C. J., et al. (1995). Family accommodation in obsessive compulsive disorder. American Journal of Psychiatry, 152, 441–443.  https://doi.org/10.1176/ajp.152.3.441.CrossRefPubMedGoogle Scholar
  13. Calvocoressi, L., Mazure, C., Kasl, S. V., Skolnick, J., Fisk, D., Vegso, S. J., et al. (1999). Family accommodation of obsessive–compulsive symptoms: Instrument development and assessment of family behavior. Journal of Nervous and Mental Disease, 187, 636–642.  https://doi.org/10.1097/00005053-199910000-00008.CrossRefPubMedGoogle Scholar
  14. Caporino, N. E., Morgan, J., Beckstead, J., Phares, V., Murphy, T. K., & Storch, E. A. (2012). A structural equation analysis of family accommodation in pediatric obsessive–compulsive disorder. Journal of Abnormal Child Psychology, 40, 133–143.  https://doi.org/10.1007/s10802-011-9549-8.CrossRefPubMedGoogle Scholar
  15. Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale: Erlbaum.Google Scholar
  16. Comer, J. S., Furr, J. M., Kerns, C. E., Miguel, E., Coxe, S., Elkins, R. M., et al. (2017). Internet-delivered, family-based treatment for early-onset OCD: A pilot randomized trial. Journal of Consulting and Clinical Psychology, 85, 178–186.  https://doi.org/10.1037/ccp0000155.CrossRefPubMedGoogle Scholar
  17. Duval, S., & Tweedie, R. (2000a). A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis. Journal of the American Statistical Association, 95, 89–98.  https://doi.org/10.1080/01621459.2000.10473905.CrossRefGoogle Scholar
  18. Duval, S., & Tweedie, R. (2000b). Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 56, 455–463.  https://doi.org/10.2307/2676988.CrossRefPubMedPubMedCentralGoogle Scholar
  19. Farrell, L. J., Hourigan, D., & Waters, A. M. (2013). Do mothers enhance responsibility in children with obsessive-compulsive disorder? A preliminary study of mother-child interactions during a problem solving discussion. Journal of Obsessive-Compulsive and Related Disorders, 2, 78–84.  https://doi.org/10.1016/j.jocrd.2012.12.001.CrossRefGoogle Scholar
  20. Farrell, L. J., Oar, E. L., Waters, A. M., McConnell, H., Tiralongo, E., Garbharran, V., et al. (2016). Brief intensive CBT for OCD with E-therapy maintenance. Journal of Anxiety Disorders, 42, 85–94.  https://doi.org/10.1016/j.janxdis.2016.06.005.CrossRefPubMedGoogle Scholar
  21. Farrell, L. J., Schlup, B., & Boschen, M. J. (2010). Cognitive–behavioral treatment of childhood obsessive-compulsive disorder in community-based clinical practice: Clinical significance and benchmarking against efficacy. Behaviour Research and Therapy, 48(5), 409–417.CrossRefGoogle Scholar
  22. Farrell, L. J., Waters, A. M., Milliner, E. L., & Ollendick, T. H. (2012). Comorbidity and treatment response in obsessive-compulsive disorder: A pilot study of group cognitive-behavioral treatment. Psychiatry Research, 199, 115–123.  https://doi.org/10.1016/j.psychres.2012.04.035.CrossRefPubMedGoogle Scholar
  23. Fernández de la Cruz, L., Barrow, F., Bolhuis, K., Krebs, G., Volz, C., Nakatani, E., et al. (2013). Sexual obsessions in obsessive-compulsive disorder: Clinical characteristics and treatment outcomes. Depression and Anxiety, 30(8), 732–740.CrossRefGoogle Scholar
  24. Fernández de la Cruz, L., Jassi, A., Krebs, G., Clark, B., & Mataix-Cols, D. (2015). Phenomenology and treatment outcomes in children and adolescents from ethnic minorities with obsessive–compulsive disorder. Journal of Obsessive-Compulsive and Related Disorders, 4, 30–36.  https://doi.org/10.1016/j.jocrd.2014.11.003.CrossRefGoogle Scholar
  25. Fischer, D. J., Himle, J. A., & Hanna, G. L. (1998). Group behavioral therapy for adolescents with obsessive-compulsive disorder: Preliminary outcomes. Research on Social Work Practice, 8, 629–636.  https://doi.org/10.1177/104973159800800601.CrossRefGoogle Scholar
  26. Flessner, C. A., Freeman, J. B., Sapyta, J., Garcia, A., Franklin, M. E., March, J. S., et al. (2011). Predictors of parental accommodation in obsessive-compulsive disorder: Findings from the pediatric obsessive compulsive disorder treatment Study (POTS) trial. Journal of the American Academy of Child and Adolescent Psychiatry, 50(7), 716–725.CrossRefGoogle Scholar
  27. Flessner, C. A., Sapyta, J., Garcia, A., Freeman, J. B., Franklin, M. E., Foa, E., et al. (2009). Examining the psychometric properties of the family accommodation scale-parent-report (FAS-PR). Journal of Psychopathology and Behavioral Assessment, 31, 38–46.  https://doi.org/10.1007/s10862-010-9196-3.CrossRefPubMedPubMedCentralGoogle Scholar
  28. Franklin, M. E., Kozac, M. J., Cashman, L. A., Coles, M. E., Reingold, B. A., & Foa, E. B. (1998). Cognitive-behavioural treatment of pediatric obsessive compulsive disorder: An open clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 412–419.  https://doi.org/10.1097/00004583-199804000-00019.CrossRefPubMedGoogle Scholar
  29. Freeman, J., Benito, K., Herren, J., Kemp, J., Sung, J., Georgiadis, G., et al. (2018). Evidence base update of psychosocial treatments for pediatric obsessive-compulsive disorder: Evaluating, improving, and transporting what works. Journal of Clinical Child and Adolescent Psychology, 47, 669–698.  https://doi.org/10.1080/15374416.2018.1496443.CrossRefPubMedGoogle Scholar
  30. Freeman, J. B., Garcia, A. M., Coyne, L., Ale, C., Przeworski, A., Himle, M., et al. (2008). Early childhood OCD: Preliminary findings from a family-based cognitive-behavioral approach. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 593–602.  https://doi.org/10.1097/CHI.0b013e31816765f9.CrossRefPubMedPubMedCentralGoogle Scholar
  31. Freeman, J., Garcia, A., Frank, H., Benito, K., Conelea, C., Walther, M., et al. (2014a). Evidence base update for psychosocial treatments for pediatric obsessive-compulsive disorder. Journal of Clinical Child and Adolescent Psychology, 43, 7–26.  https://doi.org/10.1080/15374416.2013.804386.CrossRefPubMedGoogle Scholar
  32. Freeman, J., Sapyta, J., Garcia, A., Compton, S., Khanna, M., Flessner, C., et al. (2014b). Family-based treatment of early childhood obsessive-compulsive disorder: The pediatric obsessive-compulsive disorder treatment study for young children (POTS Jr)-A randomized clinical trial. Journal of the American Medical Association Psychiatry, 71, 689–698.  https://doi.org/10.1001/jamapsychiatry.2014.170.CrossRefPubMedGoogle Scholar
  33. Garcia, A. M., Sapyta, J. J., Moore, P. S., Freeman, J. B., Franklin, M. E., March, J. S., et al. (2010). Predictors and moderators of treatment outcome in pediatric obsessive compulsive treatment study (POTS 1). Journal of the American Academy of Child and Adolescent Psychiatry, 49, 1024–1033.  https://doi.org/10.1016/j.jaac.2010.06.013.CrossRefPubMedPubMedCentralGoogle Scholar
  34. Geller, D., & March, J. (2012). Practice parameter for the assessment and treatment of children and adolescents with obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 98–113.CrossRefGoogle Scholar
  35. Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., et al. (1989). The Yale-Brown obsessive compulsive scale. I.: Development, use and reliability. Archives of General Psychiatry, 46, 1006–1011.  https://doi.org/10.1001/archpsyc.1989.01810110048007.CrossRefPubMedGoogle Scholar
  36. Gorenstein, G., Gorenstein, C., de Oliveira, M. C., Asbahr, F. R., & Shavitt, R. G. (2015). Child-focused treatment of pediatric OCD affects parental behavior and family environment. Psychiatry Research, 30, 161–166.  https://doi.org/10.1016/j.psychres.2015.07.050.CrossRefGoogle Scholar
  37. Haciomeroglu, B., & Karanci, A. N. (2013). Perceived parental rearing behaviours, responsibility attitudes and life events as predictors of obsessive compulsive symptomatology: Test of a cognitive model. Behavioural and Cognitive Psychotherapy, 42, 641–652.  https://doi.org/10.1017/S1352465813000581.CrossRefPubMedGoogle Scholar
  38. Heyman, E., Fombonne, H., Simmons, T. F., & Meltzer, R. G. (2003). Prevalence of obsessive-compulsive disorder in the British nationwide survey of child mental health. International Review of Psychiatry, 15, 178–184.  https://doi.org/10.1192/bjp.179.4.324.CrossRefPubMedGoogle Scholar
  39. Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., et al. (2011). The cochrane collaboration’s tool for assessing risk of bias in randomised trials. BMJ, 343, d5928.  https://doi.org/10.1136/bmj.d5928.CrossRefPubMedPubMedCentralGoogle Scholar
  40. Higgins, J. P. T., & Green, S. (Eds.). (2011). Cochrane Handbook for Systematic Reviews of Interventions. New Jersey: John Wiley & Sons.Google Scholar
  41. Hudson, J. L., Rapee, R. M., Lyneham, H. J., McLellan, L. F., Wuthrich, V. M., & Schniering, C. A. (2015). Comparing outcomes for children with different anxiety disorders following cognitive behavioural therapy. Behaviour Research and Therapy, 72, 30–37.  https://doi.org/10.1016/j.brat.2015.06.007.CrossRefPubMedGoogle Scholar
  42. Iniesta-Sepúlveda, M., Rosa-Alcázar, A. I., Sánchez-Meca, J., Parada-Navas, J. L., & Rosa-Alcázar, A. (2017). Cognitive-behavioral high parental involvement treatments for pediatric obsessive-compulsive disorder: A meta-analysis. Journal of Anxiety Disorders, 49, 53–64.  https://doi.org/10.1016/j.janxdis.2017.03.010.CrossRefPubMedGoogle Scholar
  43. Kagan, E. R., Frank, H. E., & Kendall, P. C. (2017). Accommodation in youth with OCD and anxiety. Clinical Psychology: Science and Practice, 24, 78–98.  https://doi.org/10.1111/cpsp.12186.CrossRefGoogle Scholar
  44. Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 980–988.  https://doi.org/10.1097/00004583-199707000-00021.CrossRefPubMedGoogle Scholar
  45. Lavell, C. H., Farrell, L. J., Waters, A. M., & Cadman, J. (2016). Predictors of treatment response to group cognitive behavioural therapy for pediatric obsessive-compulsive disorder. Psychiatry Research, 245, 186–193.  https://doi.org/10.1016/j.psychres.2016.08.033.CrossRefPubMedGoogle Scholar
  46. Lebowitz, E. R., Panza, K. E., Su, J., & Bloch, M. H. (2012). Family accommodation in obsessive-compulsive disorder. Expert Review of Neurotherapeutics, 12, 229–238.  https://doi.org/10.1586/ern.11.200.CrossRefPubMedPubMedCentralGoogle Scholar
  47. Lebowitz, E. R., Scharfstein, L. A., & Jones, J. (2014). Comparing family accommodation in pediatric obsessive-compulsive disorder, anxiety disorders, and nonanxious children. Depression and Anxiety, 00, 1–8.  https://doi.org/10.1002/da.22251.CrossRefGoogle Scholar
  48. Lewin, A. B., Park, J. M., Jones, A. M., Crawford, E. A., De Nadai, A. S., Menzel, J., et al. (2014). Family-based exposure and response prevention therapy for preschool-aged children with obsessive-compulsive disorder: A pilot randomized controlled trial. Behaviour Research and Therapy, 56, 30–38.  https://doi.org/10.1016/j.brat.2014.02.001.CrossRefPubMedGoogle Scholar
  49. Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration”. PLOS Medicine, 6, e1000100.  https://doi.org/10.1371/journal.pmed.1000100.CrossRefPubMedPubMedCentralGoogle Scholar
  50. March, J. S., & Mulle, K. (1998). OCD in children and adolescents: a cognitive-behavioral treatment manual. New York: Guilford Press.Google Scholar
  51. March, J. S., Mulle, K., & Herbel, B. (1994). Behavioral psychotherapy for children and adolescents with obsessive-compulsive disorder: An open trial of a new protocol driven treatment package. Journal of the American Academy of Child and Adolescent Psychiatry, 33(3), 333–341.CrossRefGoogle Scholar
  52. Martin, J., & Thienemann, M. (2005). Group cognitive-behavior therapy with family involvement for middle-school-age children with obsessive-compulsive disorder: A pilot study. Child Psychiatry and Human Development, 36, 113–127.  https://doi.org/10.1007/s10578-005-3496-y.CrossRefPubMedGoogle Scholar
  53. Mathieu, S. L., Farrell, L. J., Waters, A. M., & Lightbody, J. (2015). An observational study of parent–child behaviours in paediatric OCD: Examining the origins of inflated responsibility. Journal of Obsessive-Compulsive and Related Disorders, 6, 132–143.  https://doi.org/10.1016/j.jocrd.2015.07.004.CrossRefGoogle Scholar
  54. Merlo, L. J., Lehmkuhl, H. D., Geffken, G. R., & Storch, E. A. (2009). Decreased family accommodation associated with improved therapy outcome in pediatric obsessive-compulsive disorder. Journal of Consulting and Clinical Psychology, 77, 355–360.  https://doi.org/10.1037/a0012652.CrossRefPubMedPubMedCentralGoogle Scholar
  55. Merlo, L. J., Storch, E. A., Lehmkuhl, H. D., Jacob, M. L., Murphy, T. K., Goodman, W. K., et al. (2010). Cognitive-behavioral therapy plus motivational interviewing improves outcome for pediatric obsessive-compulsive disorder: A preliminary study. Cognitive Behaviour Therapy, 39(1), 24–27.CrossRefGoogle Scholar
  56. Nakatani, E., Krebs, G., Micali, N., Turner, C., Heyman, I., & Mataix-Cols, D. (2011). Children with very early onset obsessive- compulsive disorder: clinical features and treatment outcome. Journal of Child Psychology and Psychiatry, 52, 1261–1268.  https://doi.org/10.1111/j.1469-7610.2011.02434.x.CrossRefPubMedGoogle Scholar
  57. Olatunji, B. O., Davis, M. L., Powers, M. B., & Smits, J. A. J. (2013). Cognitive-behavioral therapy for obsessive-compulsive disorder: A meta-analysis of treatment outcome and moderators. Journal of Psychiatric Research, 47, 33–41.  https://doi.org/10.1016/j.jpsychires.2012.08.020.CrossRefPubMedGoogle Scholar
  58. Pediatric OCD Treatment Study (POTS) Team. (2004). Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: The Pediatric OCD Treatment Study (POTS) randomized controlled trial. Journal of the American Medical Association, 292, 1969–1976.  https://doi.org/10.1001/jama.292.16.1969.CrossRefGoogle Scholar
  59. Peris, T. S., & Piacentini, J. (2013). Optimizing treatment for complex cases of childhood obsessive compulsive disorder: A preliminary trial. Journal of Clinical Child & Adolescent Psychology, 42, 1–8.  https://doi.org/10.1080/15374416.2012.673162.CrossRefGoogle Scholar
  60. Peris, T. S., & Piacentini, J. (2016). Helping families manage childhood OCD: Decreasing conflict and increasing positive interaction, Therapist Guide (Programs That Work). New York: Oxford University Press.CrossRefGoogle Scholar
  61. Peris, T. S., Rozenman, M. S., Sugar, C. A., McCracken, J. T., & Piacentini, J. (2017). Targeted family intervention for complex cases of pediatric obsessive-compulsive disorder: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 56, 1034–1042.  https://doi.org/10.1016/j.jaac.2017.10.008.CrossRefPubMedPubMedCentralGoogle Scholar
  62. Peris, T. S., Sugar, C. A., Bergman, R. L., Chang, S., Langley, A., & Piacentini, J. (2012a). Family factors predict treatment outcome for pediatric obsessive-compulsive disorder. Journal of Consulting and Clinical Psychology, 80, 255–263.  https://doi.org/10.1037/a0027084.CrossRefPubMedPubMedCentralGoogle Scholar
  63. Peris, T. S., Yadegar, M., Asarnow, J. R., & Piacentini, J. (2012b). Pediatric obsessive compulsive disorder: Family climate as a predictor of treatment outcome. Journal of Obsessive-Compulsive and Related Disorders, 1, 267–273.  https://doi.org/10.1016/j.jocrd.2012.07.003.CrossRefGoogle Scholar
  64. Piacentini, J., Bergman, L., Chang, S., Langley, A., Peris, T., Woos, J. J., et al. (2011). Controlled comparison of family cognitive behavioral therapy and psychoeducation/relaxation training for child obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 1149–1161.  https://doi.org/10.1016/j.jaac.2011.08.003.CrossRefPubMedPubMedCentralGoogle Scholar
  65. Piacentini, J., Bergman, R. L., Jacobs, C., McCracken, J. T., & Kretchman, J. (2002). Open trial of cognitive behavior therapy for childhood obsessive-compulsive disorder. Journal of Anxiety Disorders, 16, 207–219.  https://doi.org/10.1016/S0887-6185(02)00096-8.CrossRefPubMedGoogle Scholar
  66. Piacentini, J., Bergman, L., Keller, M., & McCracken, J. (2003). Functional impairment in children and adolescents with obsessive-compulsive disorder. Journal of Child and Adolescent Psychopharmacology, 13(2), 61–69.CrossRefGoogle Scholar
  67. Pietrefesa, A. S., Schofield, C. A., Whiteside, S. P., Sochting, I., & Coles, M. E. (2010). Obsessive beliefs in youth with OCD and their mothers. Journal of Cognitive Psychotherapy, 24, 187–197.  https://doi.org/10.1891/0889-8391.24.3.187.CrossRefGoogle Scholar
  68. Rapoport, J., Inoff-Germian, G., Weissman, M., Greenwald, S., Narrow, W. E., Jensen, P. S., et al. (2000). Childhood obsessive-compulsive disorder in the NIMH MECA Study: parent versus child identification of cases. Methods for the epidemiology of child and adolescent mental disorders. Journal of Anxiety, 14, 535–548.  https://doi.org/10.1016/S0887-6185(00)00048-7.CrossRefGoogle Scholar
  69. Reynolds, S. A., Bowers, G., Norton, E., Clark, S., Smith, H., Langdon, P. E., et al. (2013). Randomized controlled trial of parent-enhanced CBT compared with individual CBT for obsessive-compulsive disorder in young people. Journal of Consulting and Clinical Psychology, 81, 1021–1026.  https://doi.org/10.1037/a0034429.CrossRefPubMedGoogle Scholar
  70. Rosa-Alcázar, A. I., Sánchez-Meca, J., Rosa-Alcázar, A., Iniesta-Sepúlveda, M., Olivares-Rodríguez, J., & Parada-Navas, J. L. (2015). Psychological treatment of obsessive-compulsive disorder in children and adolescents: A meta-analysis. Spanish Journal of Psychology, 18, 1–22.CrossRefGoogle Scholar
  71. Rosenthal, R. (1979). The “file drawer problem” and tolerance for null results. Psychological Bulletin, 86, 638–641.  https://doi.org/10.1037/0033-2909.86.3.638.CrossRefGoogle Scholar
  72. Rosenthal, R. (1993). Meta-analytic procedures for social research. CA: Sage.Google Scholar
  73. Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., et al. (1997). Children’s Yale-Brown obsessive-compulsive scale: Reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 844–852.  https://doi.org/10.1097/00004583-199706000-00023.CrossRefPubMedGoogle Scholar
  74. Scahill, L., Vitulano, L. A., Brenner, E. M., Lynch, K. A., & King, R. A. (1996). Behavioral therapy in children and adolescents with obsessive-compulsive disorder: A pilot study. Journal of Child and Adolescent Psychopharmacology, 6, 191–202.  https://doi.org/10.1089/cap.1996.6.191.CrossRefPubMedGoogle Scholar
  75. Selles, R. R., Belschner, L., Negreiros, J., Lin, S., Schuberth, D., McKenney, K., et al. (2018). Group family-based cognitive behavioral therapy for pediatric obsessive compulsive disorder: Global outcomes and predictors of improvement. Psychiatry Research, 260, 116–122.  https://doi.org/10.1016/j.psychres.2017.11.041.CrossRefPubMedGoogle Scholar
  76. Silverman, W. K., & Albano, A. M. (1996). The anxiety disorders interview schedule for children for DSM–IV: Child and parent versions. San Antonio: Psychological Corporation.Google Scholar
  77. Storch, E. A., Caporino, N. E., Morgan, J. R., Lewin, A. B., Rojas, A., Brauer, L., et al. (2011). Preliminary investigation of web-camera delivered cognitive-behavioral therapy for youth with obsessive-compulsive disorder. Psychiatry Research, 189, 407–412.  https://doi.org/10.1016/j.psychres.2011.05.047.CrossRefPubMedGoogle Scholar
  78. Storch, E. A., Geffken, G. R., Merlo, L. J., Mann, G., Duke, D., Munson, M., et al. (2007). Family-based cognitive-behavioral therapy for pediatric obsessive-compulsive disorder: Comparison of intensive and weekly approaches. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 469–478.  https://doi.org/10.1097/chi.0b013e31803062e7.CrossRefPubMedGoogle Scholar
  79. Storch, E. A., Larson, M. J., Muroff, J., Caporino, N., Geller, D., Reid, J. M., et al. (2010a). Predictors of functional impairment in pediatric obsessive–compulsive disorder. Journal of Anxiety Disorders, 24, 275–283.  https://doi.org/10.1016/j.janxdis.2009.12.004.CrossRefPubMedGoogle Scholar
  80. Storch, E. A., Lehmkuhl, H. D., Ricketts, E., Geffken, G. R., Marien, W., & Murphy, T. K. (2010b). An open trial of intensive family based cognitive-behavioral therapy in youth with obsessive-compulsive disorder who are medication partial responders or nonresponders. Journal of Clinical Child & Adolescent Psychology, 39, 260–268.  https://doi.org/10.1080/15374410903532676.CrossRefGoogle Scholar
  81. Storch, E. A., Merlo, L. J., Larson, M. J., Marien, W. E., Geffken, G. R., Jacob, M. L., et al. (2008). Clinical features associated with treatment-resistant pediatric obsessive–compulsive disorder. Comprehensive Psychiatry, 49, 35–42.  https://doi.org/10.1016/j.comppsych.2007.06.009.CrossRefPubMedGoogle Scholar
  82. Strauss, C., Hale, L., & Stobie, B. (2015). A meta-analytic review of the relationship between family accommodation and OCD symptom severity. Journal of Anxiety Disorders, 33, 95–102.  https://doi.org/10.1016/j.janxdis.2015.05.006.CrossRefPubMedGoogle Scholar
  83. Sukhodolsky, D. G., Gorman, B. S., Scahill, L., Findley, D., & McGuire, J. (2013). Exposure and response prevention with or without parent management training for children with obsessive-compulsive disorder complicated by disruptive behavior: A multiple-baseline across-responses design study. Journal of Anxiety Disorders, 27, 298–305.  https://doi.org/10.1016/j.janxdis.2013.01.005.CrossRefPubMedGoogle Scholar
  84. Thompson-Hollands, J., Edson, A., Tompson, M. C., & Comer, J. S. (2014). Family involvement in the psychological treatment of obsessive-compulsive disorder: A meta-analysis. Journal of Family Psychology, 28, 287–298.  https://doi.org/10.1037/a0036709.CrossRefPubMedPubMedCentralGoogle Scholar
  85. Timpano, K. R., Keough, M. E., Mahaffey, B., Schmidt, N. B., & Abramowitz, J. (2010). Parenting and obsessive compulsive symptoms: Implications of authoritarian parenting. Journal of Cognitive Psychotherapy, 24, 151–164.CrossRefGoogle Scholar
  86. Turner, C., Heyman, I., Futh, A., & Lovell, K. (2009). A pilot study of telephone cognitive-behavioural therapy for obsessive-compulsive disorder in young people. Behavioural and Cognitive Psychotherapy, 37, 469–474.  https://doi.org/10.1017/S1352465809990178.CrossRefPubMedGoogle Scholar
  87. Turner, C., Mataix-Cols, D., Lovell, K., Krebs, G., Lang, K., Byford, S., et al. (2014). Telephone cognitive-behavioral therapy for adolescents with obsessive-compulsive disorder: A randomized controlled non-inferiority trial. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 1298–1307.  https://doi.org/10.1016/j.jaac.2014.09.012.CrossRefPubMedPubMedCentralGoogle Scholar
  88. Valleni-Basile, L. A., Garrison, C. Z., Jackson, K. L., Waller, J. L., McKeown, R. E., Addy, C. L., et al. (1995). Family and psychosocial predictors of obsessive compulsive disorder in a community sample of young adolescents. Journal of Child and Family Studies, 4, 193–206.  https://doi.org/10.1097/00004583199407000-00002.CrossRefGoogle Scholar
  89. Waters, T. L., Barrett, P. M., & March, J. S. (2001). Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: Preliminary findings. American Journal of Psychotherapy, 55, 372–387.CrossRefGoogle Scholar
  90. Whiteside, S. P., & Jacobsen, A. B. (2010). An uncontrolled examination of a 5-day intensive treatment for pediatric OCD. Behavior Therapy, 41, 414–422.  https://doi.org/10.1016/j.beth.2009.11.003.CrossRefPubMedGoogle Scholar
  91. Whiteside, S. P., McKay, D., De Nadai, A. S., Tiede, M. S., Ale, C. M., & Storch, E. A. (2014). A baseline controlled examination of a 5-day intensive treatment for pediatric obsessive-compulsive disorder. Psychiatry Research, 220, 441–446.  https://doi.org/10.1016/j.psychres.2014.07.006.CrossRefPubMedGoogle Scholar
  92. Wu, M. S., McGuire, J. F., Martino, C., Phares, V., Selles, R. R., & Storch, E. A. (2016). A meta-analysis of family accommodation and OCD symptom severity. Clinical Psychology Review, 45, 34–44.  https://doi.org/10.1016/j.cpr.2016.03.003.CrossRefPubMedGoogle Scholar
  93. Zohar, A. H. (1999). The epidemiology of obsessive- compulsive disorder in children and adolescents. Child and Adolescent Psychiatric Clinics of North America, 8, 445–460.  https://doi.org/10.1016/S1056-4993(18)30163-9.CrossRefPubMedGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Clinical Psychology Unit, School of Psychology (M02F)The University of SydneySydneyAustralia

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