Oxidative Esterification of Homologous 1,3-Propanediols
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The oxidative esterification of a homologous series of diols (1,3-propanediol,2-methyl-propanediol and 2,2-dimethyl-1,3-propanediol) with methanol has been investigated using titania-supported gold, palladium and gold–palladium catalysts using molecular oxygen. The gold–palladium catalysts showed the highest activity and 1,3-propanediol was the most reactive while the additional methyl groups decreased the reactivity. However, it is possible to achieve high selectivity to methyl 3-hydroxypropionate and 2-methyl-3-hydroxyisobutyrate by mono-oxidations.
KeywordsGold catalysis Gold palladium alloy nanoparticles Oxidative esterification Diol oxidation
This work formed part of the Glycerol Challenge and Tennants Fine Chemicals Ltd and the Technology Strategy Board are thanked for their financial support. This project is co-funded by the Technology Strategy Boards Collaborative Research and Development programme, following an open competition. The Technology Strategy Board is an executive body established by the Government to drive innovation. It promotes and invests in research, development and the exploitation of science, technology and new ideas for the benefit of business—increasing sustainable economic growth in the UK and improving quality of life. For more information visit www.innovateuk.org.
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