A pharmacoeconomic analysis of the collection and preservation of samples in the biobank of the “Instituto Nacional de Cancerología” in Mexico City
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In this work we estimated the budgetary impact of the samples produced by the biobank of the “Instituto Nacional de Cancerología” (BT-INCan) to set a recuperation fee from the perspective of the Health Ministry of Mexico. The study is an observational retrospective review of the direct medical costs (DMCs) of the processes involved in cryopreservation of the samples collected, on a per sample basis, including materials, laboratory tests, personnel, and administrative costs. Materials and labor costs were determined by information collected from the BT-INCan. DMCs were provided depending on the type of sample: plasma, tissue and biopsy; they were calculated according to the process required to preserve them. Sensitivity analysis was performed using bootstrap. Recuperation costs ranged from 130 to 155 USD. Costs were considered on a 5-year time frame for the maintenance per sample, which is the average time that a sample is kept in the BT-INCan. The cost analysis is perceived as an approximation to the most adequate recuperation fee per sample needed to guarantee the correct development of the BT-INCan. This work provides a basis and valuable information about costs, to enable several health institutions to strategically plan and manage a biobank or even motivate to establish their own biobank.
KeywordsBiobank Pharmacoeconomics Tumor sample preservation Preservation costs Instituto Nacional de Cancerología Tumor Biorepository National cancer control institutes
The authors appreciate the support of Pedro Arellano, Hector Romero and Gabriel Molina, from the Accounting Department, and Silvia García for secretarial support, all of them from the Instituto Nacional de Cancerología, Mexico.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- Caboux E, Plymoth A, Hainaut P (2007) Common minimum technical standards and protocols for biological resource centres dedicated to cancer research. WorkGroup report 2. IARCGoogle Scholar
- Campbell LD, Betsou F, Garcia DL, Giri JG, Pitt KE, Pugh RS, Sexton KC, Skubitz AP, Somiari SB (2012) Development of the ISBER best practices for repositories: collection, storage, retrieval and distribution of biological materials for research. Biopreserv Biobank 10:232–233CrossRefPubMedGoogle Scholar
- Enriquez V, Ruiz-Godoy L (2017) Manual de procedimientos del Biobanco del Instituto Nacional de Cancerología. UnpublishedGoogle Scholar
- Moore HM, Kelly AB, Jewell SD, McShane LM, Clark DP, Greenspan R, Hayes DF, Hainaut P, Kim P, Mansfield EA, Potapova O, Riegman P, Rubinstein Y, Seijo E, Somiari S, Watson P, Weier HU, Zhu C, Vaught J (2011) Biospecimen reporting for improved study quality (BRISQ). Cancer Cytopathol 119:92–101CrossRefPubMedGoogle Scholar