Cardiovascular Drugs and Therapy

, Volume 30, Issue 2, pp 215–228 | Cite as

Contrast-Induced Acute Kidney Injury: An Update

  • George Chalikias
  • Ioannis Drosos
  • Dimitrios N. Tziakas
REVIEW ARTICLE
First Online:

Abstract

Contrast-induced acute kidney injury (CI-AKI) is defined as an abrupt deterioration in renal function associated with the administration of iodinated contrast media. This type of acute kidney injury is frequently encountered as a complication of percutaneous coronary intervention (PCI) and is associated with adverse short- and long-term outcomes including mainly mortality, cardiovascular morbidity and prolongation of hospitalization. The incidence of CI-AKI after PCI ranges from 2 to 20 % according to baseline kidney function. It may also range according to the clinical setting, being higher after emergency PCI. The primary manifestation is a small decline in kidney function, occurring 1 to 3 days after the procedure. Kidney function usually returns to preexisting levels within 7 days. Incidence of acute renal failure requiring dialysis following PCI is rare (<1 %). The present article aims to review up-to-date published data concerning diagnosis, definition, epidemiology and prognosis of this novel in-hospital epidemic.

Keywords

Contrast induced nephropathy Percutaneous coronary intervention Acute kidney injury Contrast media 
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Supplementary material

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • George Chalikias
    • 1
  • Ioannis Drosos
    • 1
  • Dimitrios N. Tziakas
    • 1
  1. 1.University Cardiology Department, Medical SchoolDemocritus University of ThraceAlexandroupolisGreece

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