Cancer and Metastasis Reviews

, Volume 29, Issue 3, pp 395–404

Do nutraceutics play a role in the prevention and treatment of colorectal cancer?

  • Brian Markle
  • Elizabeth J. May
  • Adhip P. N. Majumdar


Colorectal cancer is the third most common cancer worldwide with a 5-year survival of 50%. Current chemotherapeutic regimens used for advanced colorectal cancer provide an average survival of approximately 20 months. Non-toxic agents such as nutraceutics and supplements have been shown to aid in the prevention and adjuvant treatment of colorectal cancer. This article will discuss the epidemiology, progression, prevention, treatment, and recurrence of colorectal cancer and the role of nutraceutics and supplements in the treatment process.


Colorectal cancer Nutraceutics Curcumin Folate Vitamin D Calcium 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Brian Markle
    • 2
  • Elizabeth J. May
    • 2
  • Adhip P. N. Majumdar
    • 1
    • 2
    • 3
    • 4
  1. 1.Veterans Affairs Medical CenterWayne State UniversityDetroitUSA
  2. 2.Department of Internal MedicineWayne State UniversityDetroitUSA
  3. 3.Karmanos Cancer InstituteWayne State UniversityDetroitUSA
  4. 4.VA Medical Center, Research ServiceDetroitUSA

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