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Correlation between left ventricular myocardial strain and left ventricular geometry in healthy adults: a cardiovascular magnetic resonance-feature tracking study

  • Zhen Zhang
  • Qiaozhi Ma
  • Lizhen Cao
  • Zhiwei Zhao
  • Jun Zhao
  • Qing Lu
  • Linan Zeng
  • Mingzhu Zhang
  • Gerald M. Pohost
  • Kuncheng LiEmail author
Original Paper
  • 17 Downloads

Abstract

This study was aimed to investigate the correlation between left ventricular (LV) myocardial strain and LV geometry in healthy adults using cardiovascular magnetic resonance-feature tracking (CMR-FT). 124 gender-matched healthy adults who underwent healthy checkup using CMR cine imaging were retrospectively analyzed. Peak global radial, circumferential, longitudinal strain (GRS, GCS and GLS) for left ventricle were measured. LV geometry was assessed by the ratio of LV mass (LVM) and end-diastolic volume (EDV). GRS, GCS and GLS were 34.18 ± 6.71%, − 22.17 ± 2.28%, − 14.76 ± 2.39% for men, and 33.40 ± 6.95%, − 22.49 ± 2.27%, − 15.72 ± 2.36% for women. Multiple linear regression showed that LVM/EDV was associated with decreased GLS (β = − 0.297, p = 0.005), but was not significantly associated with GRS and GCS (both p > 0.05). There was an increase in the magnitude of GRS, GCS and GLS with advancing age (β = 0.254, β = 0.466 and β = 0.313, all p < 0.05). Greater BMI was associated with decreased GRS, GCS and GLS (β = − 0.232, β = − 0. 249 and β = − 0.279, all p < 0.05). In conclusion, compared with GRS and GCS, GLS is more sensitive to assess LV concentric remodeling in healthy adults. GRS, GCS and GLS are all independently positively associated with age and negatively associated with BMI. Sex-based LV strain reference values for healthy Chinese adults are established.

Keywords

Cardiovascular magnetic resonance-feature tracking Left ventricular geometry Myocardial strain 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  • Zhen Zhang
    • 1
  • Qiaozhi Ma
    • 2
  • Lizhen Cao
    • 1
  • Zhiwei Zhao
    • 3
  • Jun Zhao
    • 3
  • Qing Lu
    • 3
  • Linan Zeng
    • 3
  • Mingzhu Zhang
    • 3
  • Gerald M. Pohost
    • 3
    • 4
  • Kuncheng Li
    • 1
    • 3
    Email author
  1. 1.Department of Radiology, Xuanwu HospitalCapital Medical UniversityBeijingChina
  2. 2.Department of Magnetic Resonance, the Third Medical CentreChinese People’s Liberation Army General HospitalBeijingChina
  3. 3.Xiamen Zhouxin Medical Imaging Diagnostic CentreXiamenChina
  4. 4.Keck School of MedicineUniversity of Southern CaliforniaLos AngelesUSA

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