In-vivo assessment of normal T1 values of the right-ventricular myocardium by cardiac MRI

  • N. Kawel-Boehm
  • T. Dellas Buser
  • A. Greiser
  • O. Bieri
  • J. Bremerich
  • F. Santini
Original Paper


To test feasibility of myocardial T1 mapping of the right ventricle (RV) at systole when myocardium is more compact and to determine the most appropriate imaging plane. 20 healthy volunteers (11 men; 33 ± 8 years) were imaged on a 1.5T scanner (MAGNETOM Avanto, Siemens AG, Erlangen, Germany). A modified look-locker inversion-recovery sequence was acquired at mid-ventricular short axis (SAX), as horizontal long-axis view and as transversal view at systole (mean trigger time 363 ± 37 ms). Myocardial T1 time of the left-ventricular and RV myocardium was measured within a region of interest (ROI) on generated T1-maps. The most appropriate imaging plane for the RV was determined by the ability to draw a ROI including the largest amount of myocardium without including adjacent tissue or blood. At systole, when myocardium is thicker, measurements of the RV myocardium were feasible in 18/20 subjects. Average size of the ROI was 0.42 ± 0.28 cm2. In 10/18 subjects, short axis was the most appropriate imaging plane to obtain measurements (p = 0.034). Average T1 time of the RV myocardium was 1,016 ± 61 ms, and average T1 of the left-ventricular (LV) was 956 ± 25 ms (p < 0.001). T1 mapping of the RV myocardium is feasible during systole in the majority of healthy subjects but with a small ROI only. SAX plane was the optimal imaging plane in the majority of subjects. Native myocardial T1 time of the RV is significantly longer compared to the LV, which might be explained by the naturally higher collagen content of the RV.


T1 mapping Right ventricle Diffuse fibrosis 


Conflict of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • N. Kawel-Boehm
    • 1
  • T. Dellas Buser
    • 1
  • A. Greiser
    • 2
  • O. Bieri
    • 3
  • J. Bremerich
    • 1
  • F. Santini
    • 3
  1. 1.Clinic of Radiology and Nuclear MedicineUniversity of Basel HospitalBaselSwitzerland
  2. 2.Siemens AG Healthcare SectorErlangenGermany
  3. 3.Division of Radiological PhysicsUniversity of Basel HospitalBaselSwitzerland

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