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Plaque and thrombus evaluation by optical coherence tomography

  • Takashi Kubo
  • Chenyang Xu
  • Zhao Wang
  • Nienke S. van Ditzhuijzen
  • Hiram G. BezerraEmail author
Original Paper

Abstract

Intravascular Optical Coherence Tomography has been explored as an imaging tool for vessel wall and thrombus characterization. OCT enables a high resolution arterial wall imaging, and light properties allow tissue characterization. It has been proved one of the most valuable imaging modalities for the evaluation of vulnerable plaque and thrombus. OCT has a unique capacity in volumetric quantification of calcium, and unlike ultrasound, light can easily penetrate calcified plaques. Finally, this review paper will address aspects of the validation method of plaque characterization and potential pitfalls and put in perspective new approaches that may help the evolution of the field.

Keywords

Optical coherence tomography Atherosclerosis Plaque Imaging 

Notes

Conflict of interest

None.

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Copyright information

© Springer Science+Business Media, B.V. 2011

Authors and Affiliations

  • Takashi Kubo
    • 1
  • Chenyang Xu
    • 2
  • Zhao Wang
    • 3
  • Nienke S. van Ditzhuijzen
    • 4
  • Hiram G. Bezerra
    • 4
    Email author
  1. 1.Department of Cardiovascular MedicineWakayama Medical UniversityWakayamaJapan
  2. 2.Lightlab Imaging Inc.WestfordUSA
  3. 3.Department of Biomedical EngineeringCase Western Reserve UniversityClevelandUSA
  4. 4.Harrington-McLaughlin Heart and Vascular Institute, Cardiovascular Imaging Core Laboratory, University Hospitals Medical CenterCase Western Reserve University School of MedicineClevelandUSA

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