Cancer Causes & Control

, Volume 25, Issue 10, pp 1321–1327 | Cite as

Maternal consumption of coffee and tea during pregnancy and risk of childhood brain tumors: results from an Australian case–control study

  • Kathryn R. Greenop
  • Margaret Miller
  • John Attia
  • Lesley J. Ashton
  • Richard Cohn
  • Bruce K. Armstrong
  • Elizabeth Milne
Original paper

Abstract

Purpose

The causes of childhood brain tumors (CBT) are largely unknown, but gestational diet may influence this risk. The aim of this analysis was to investigate whether maternal coffee or tea consumption during pregnancy was associated with the risk of CBT.

Methods

The Australian Study of the Causes of Childhood Brain Tumours was a population-based, Australian case–control study conducted between 2005 and 2010. Case children were recruited from 10 pediatric oncology centers and control children by nationwide random-digit dialing, frequency matched to cases on the basis of age, sex and state of residence. Coffee and tea intake were assessed using a food frequency questionnaire.

Results

Data on coffee and tea consumption during pregnancy were available from 293 case mothers and 726 control mothers. Odds ratios (ORs) and confidence intervals (CIs) were calculated using multivariable unconditional logistic regression. There was little evidence of an association between gestational consumption of any coffee (OR 1.23, 95 % CI 0.92, 1.64) or tea (OR 1.00, 95 % CI 0.74, 1.36) and CBT risk. Among children aged under 5 years, the OR for any coffee consumption during pregnancy was 1.76 (95 % CI 1.09, 2.84) and for ≥2 cups per day during pregnancy was 2.52 (95 % CI 1.26, 5.04). There was little evidence that associations with coffee or tea intake differed by parental smoking status.

Conclusions

These results suggest a positive association between coffee intake ≥2 cups per day and risk of CBT in younger children, although some estimates are imprecise. There was no association between maternal tea drinking and risk of CBT.

Keywords

Brain tumors Caffeine Cancer Child Coffee Diet Pediatric Pregnancy Tea 

Supplementary material

10552_2014_437_MOESM1_ESM.doc (52 kb)
Supplementary material 1 (DOC 52 kb)

References

  1. 1.
    Australian Institute for Health and Welfare (2009) A picture of Australia’s children 2009. Cat. no. PHE 112. AIHW, CanberraGoogle Scholar
  2. 2.
    Baldwin RT, Preston-Martin S (2004) Epidemiology of brain tumors in childhood—a review. Toxicol Appl Pharmacol 199:118–131PubMedCrossRefGoogle Scholar
  3. 3.
    Plichart M, Menegaux F, Lacour B, Hartmann O, Frappaz D, Doz F, Bertozzi A-I, Defaschelles A-S, Pierre-Kahn A, Icher C, Chastagner P, Plantaz D, Rialland X, Hémon D, Clavel J (2008) Parental smoking, maternal alcohol, coffee and tea consumption during pregnancy and childhood malignant central nervous system tumours: the ESCALE study (SFCE). Eur J Cancer Prev 17:376–383PubMedCentralPubMedCrossRefGoogle Scholar
  4. 4.
    Cordier S, Iglesias MJ, Le Goaster C, Guyot MM, Mandereau L, Hemon D (1994) Incidence and risk factors for childhood brain tumors in the Ile de France. Int J Cancer 59:776–782PubMedCrossRefGoogle Scholar
  5. 5.
    Bunin GR, Kuijten RR, Buckley JD, Rorke LB, Meadows AT (1993) Relation between maternal diet and subsequent primitive neuroectodermal brain tumors in young children. N Engl J Med 329:536–541PubMedCrossRefGoogle Scholar
  6. 6.
    Bunin GR, Kuijten RR, Boesel CP, Buckley JD, Meadows AT (1994) Maternal diet and risk of astrocytic glioma in children: a report from the Childrens Cancer Group (United States and Canada). Cancer Causes Control 5:177–187PubMedCrossRefGoogle Scholar
  7. 7.
    Cano-Marquina A, Tarin JJ, Cano A (2013) The impact of coffee on health. Maturitas 75:7–21PubMedCrossRefGoogle Scholar
  8. 8.
    Yang CS, Lambert JD, Sang S (2009) Antioxidative and anti-carcinogenic activities of tea polyphenols. Arch Toxicol 83:11–21PubMedCentralPubMedCrossRefGoogle Scholar
  9. 9.
    Spector LG, Xie Y, Robison LL, Heerema NA, Hilden JM, Lange B, Felix CA, Davies SM, Slavin J, Potter JD, Blair CK, Reaman GH, Ross JA (2005) Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the Children’s Oncology Group. Cancer Epidemiol Biomarkers Prev 14:651–655PubMedCrossRefGoogle Scholar
  10. 10.
    Menegaux F, Ripert M, Hemon D, Clavel J (2007) Maternal alcohol and coffee drinking, parental smoking and childhood leukaemia: a French population-based case–control study. Paediatr Perinat Epidemiol 21:293–299PubMedCrossRefGoogle Scholar
  11. 11.
    Milne E, Royle JA, Bennett LC, de Klerk NH, Bailey HD, Bower C, Miller M, Attia J, Scott RJ, Kirby M, Armstrong BK (2011) Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case–control study. Cancer Causes Control 22:207–218PubMedCrossRefGoogle Scholar
  12. 12.
    Cheng J, Su H, Zhu R, Wang X, Peng M, Song J, Fan D (2014) Maternal coffee consumption during pregnancy and risk of childhood acute leukemia: a metaanalysis. Am J Obstet Gynecol 210:151.e1–151.e10CrossRefGoogle Scholar
  13. 13.
    Neuhouser ML (2004) Dietary flavonoids and cancer risk: evidence from human population studies. Nutr Cancer 50:1–7PubMedCrossRefGoogle Scholar
  14. 14.
    Navarro-Peran E, Cabezas-Herrera J, Garcia-Canovas F, Durrant MC, Thorneley RN, Rodriguez-Lopez JN (2005) The antifolate activity of tea catechins. Cancer Res 65:2059–2064PubMedCrossRefGoogle Scholar
  15. 15.
    Milne E, Greenop KR, Bower C, Miller M, van Bockxmeer FM, Scott RJ, de Klerk NH, Ashton LJ, Gottardo NG, Armstrong BK (2012) Maternal use of folic acid and other supplements and risk of childhood brain tumors. Cancer Epidemiol Biomarkers Prev 21:1933–1941PubMedCrossRefGoogle Scholar
  16. 16.
    Lassale C, Guilbert C, Keogh J, Syrette J, Lange K, Cox DN (2009) Estimating food intakes in Australia: validation of the Commonwealth Scientific and Industrial Research Organisation (CSIRO) food frequency questionnaire against weighed dietary intakes. J Hum Nutr Diet 22:559–566PubMedCrossRefGoogle Scholar
  17. 17.
    Holick CN, Smith SG, Giovannucci E, Michaud DS (2010) Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. Cancer Epidemiol Biomarkers Prev 19:39–47PubMedCentralPubMedCrossRefGoogle Scholar
  18. 18.
    Michaud DS, Gallo V, Schlehofer B, Tjonneland A, Olsen A, Overvad K, Dahm CC, Teucher B, Lukanova A, Boeing H, Schutze M, Trichopoulou A, Lagiou P, Kyrozis A, Sacerdote C, Krogh V, Masala G, Tumino R, Mattiello A, Bueno-de-Mesquita HB, Ros MM, Peeters PHM, van Gils CH, Skeie G, Engeset D, Parr CL, Ardanaz E, Chirlaque M-D, Dorronsoro M, Sanchez MJ, Arguelles M, Jakszyn P, Nilsson LM, Melin BS, Manjer J, Wirfalt E, Khaw K-T, Wareham N, Allen NE, Key TJ, Romieu I, Vineis P, Riboli E (2010) Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition cohort study. Am J Clin Nutr 92:1145–1150PubMedCrossRefGoogle Scholar
  19. 19.
    Malerba S, Galeone C, Pelucchi C, Turati F, Hashibe M, La Vecchia C, Tavani A (2013) A meta-analysis of coffee and tea consumption and the risk of glioma in adults. Cancer Causes Control 24:267–276PubMedCrossRefGoogle Scholar
  20. 20.
    Barone JJ, Roberts HR (1996) Caffeine consumption. Food Chem Toxicol 34:119–129PubMedCrossRefGoogle Scholar
  21. 21.
    Higdon JV, Frei B (2006) Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr 46:101–123PubMedCrossRefGoogle Scholar
  22. 22.
    Scalbert A, Williamson G (2000) Dietary intake and bioavailability of polyphenols. J Nutr 130:2073S–2085SPubMedGoogle Scholar
  23. 23.
    Lin YL, Tsai SH, Lin-Shiau SY, Ho CT, Lin JK (1999) Theaflavin-3,3′-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages. Eur J Pharmacol 367:379–388PubMedCrossRefGoogle Scholar
  24. 24.
    Nehlig A, Debry G (1994) Potential genotoxic, mutagenic and antimutagenic effects of coffee: a review. Mutat Res 317:145–162PubMedCrossRefGoogle Scholar
  25. 25.
    Pellegrini N, Serafini M, Colombi B, Del Rio D, Salvatore S, Bianchi M, Brighenti F (2003) Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. J Nutr 133:2812–2819PubMedGoogle Scholar
  26. 26.
    Arab L (2010) Epidemiologic evidence on coffee and cancer. Nutr Cancer 62:271–283PubMedCrossRefGoogle Scholar
  27. 27.
    International Agency for Research on Cancer (1999) Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide, volume 71. IARC monographs on the evaluation of carcinogenic risks to humans. World Health Organization, LyonGoogle Scholar
  28. 28.
    Food Standards Australia New Zealand (2013) Food Standards Code: Standard 1.3.3 Processing Aids. F2014C00795. Commonwealth of AustraliaGoogle Scholar
  29. 29.
    Heilmann W (2001) Technology II: decaffeination. In: Clarke RJ, Vitzthum OJ (eds) Coffee: recent developments. Blackwell Science Ltd, Oxford, pp 108–124CrossRefGoogle Scholar
  30. 30.
    Australian Bureau of Statistics (2014) 4364.0.55.007—Australian Health Survey: Nutrition First Results—foods and nutrients, 2011–12, Table 4.1 Proportion of persons consuming foods. Commonwealth of Australia. http://www.abs.gov.au/ausstats/abs@.nsf/Lookup/by%20Subject/4364.0.55.007~2011-12~Main%20Features~Non-alcoholic%20beverages~701
  31. 31.
    NSW Food Authority (2013) Food safety during pregnancy. http://www.foodauthority.nsw.gov.au/_Documents/consumer_pdf/pregnancy-brochure.pdf. Accessed 20 Jan 2014
  32. 32.
    Food Standards Australia New Zealand (2013) Pregnancy and healthy eating Food Standards Australia New Zealand http://www.foodstandards.gov.au/consumer/generalissues/pregnancy/Pages/default.aspx. Accessed 12 June 2014
  33. 33.
    Women’s and Children’s Health Network (2014) Caffeine in pregnancy. Government of South Australia. http://www.cyh.com/HealthTopics/HealthTopicDetails.aspx?p=438&np=460&id=2776. Accessed 16 June 2014
  34. 34.
    Women and Newborn Health Service (2007) Good foods for young mums-to-be. WNHS 0409 Rev 2. Government of Western Australia. http://kemh.health.wa.gov.au/brochures/consumers/wnhs0409.pdf. Accessed 19 June 2014

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Kathryn R. Greenop
    • 1
  • Margaret Miller
    • 2
  • John Attia
    • 3
    • 4
  • Lesley J. Ashton
    • 5
    • 6
  • Richard Cohn
    • 6
    • 7
  • Bruce K. Armstrong
    • 8
    • 9
  • Elizabeth Milne
    • 1
  1. 1.Telethon Kids InstituteUniversity of Western AustraliaWest PerthAustralia
  2. 2.Child Health Promotion Research Centre, School of Exercise and Health SciencesEdith Cowan UniversityMount LawleyAustralia
  3. 3.Hunter Medical Research InstituteJohn Hunter HospitalNewcastleAustralia
  4. 4.Faculty of Health, School of Medicine and Public HealthUniversity of NewcastleNewcastleAustralia
  5. 5.Research PortfolioUniversity of SydneySydneyAustralia
  6. 6.Faculty of Medicine, School of Women’s and Children’s HealthUniversity of New South WalesSydneyAustralia
  7. 7.Centre for Children’s Cancer and Blood DisordersSydney Children’s HospitalSydneyAustralia
  8. 8.Sydney School of Public HealthUniversity of SydneySydneyAustralia
  9. 9.Sax InstituteSydneyAustralia

Personalised recommendations