Cancer Causes & Control

, Volume 24, Issue 6, pp 1257–1262 | Cite as

A case–control study of lifetime occupational sitting and likelihood of breast cancer

  • Brigid M. Lynch
  • Kerry S. Courneya
  • Christine M. Friedenreich
Brief report

Abstract

Purpose

Sedentary behavior may be a unique risk factor for some cancers, including breast cancer. The objective of this study was to determine the association between lifetime occupational sitting and likelihood of breast cancer.

Methods

A case–control study of 2,452 women was conducted in Alberta, Canada, between 1995 and 1997. A comprehensive measure of lifetime physical activity assessed frequency and duration of sedentary jobs. Logistic regression estimated the odds of being diagnosed with breast cancer across quartiles of lifetime occupational sitting, by menopausal status and family history of breast cancer, and within body mass index categories and physical activity quartiles.

Results

There was no association between occupational sitting and breast cancer among pre-menopausal women and women with a family history of breast cancer. Unexpectedly, higher amounts of occupational sitting were associated with lower odds of breast cancer in post-menopausal women (top versus bottom categories of occupational sitting OR = 0.71, 95 % CI 0.52, 0.97), women without a family history of breast cancer (OR = 0.77, 95 % CI 0.60, 1.00), and women in the third highest quartile of total lifetime physical activity (OR = 0.57, 95 % CI 0.33, 0.97).

Conclusion

Occupational sitting levels were lower than would be expected in a contemporary study. Exposures may have been insufficient to make a determinable contribution to breast cancer risk.

Keywords

Breast cancer Sedentary behavior Sitting time Case–control study 

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Brigid M. Lynch
    • 1
    • 2
  • Kerry S. Courneya
    • 3
  • Christine M. Friedenreich
    • 4
    • 5
  1. 1.Physical Activity LaboratoryBaker IDI Heart and Diabetes InstituteMelbourneAustralia
  2. 2.Melbourne School of Population and Global HealthThe University of MelbourneMelbourneAustralia
  3. 3.Faculty of Physical Education and RecreationUniversity of AlbertaEdmontonCanada
  4. 4.Department of Population Health ResearchAlberta Health Services, Cancer CareCalgaryCanada
  5. 5.Departments of Oncology and Community Health Sciences, Faculty of MedicineUniversity of CalgaryCalgaryCanada

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