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Cancer Causes & Control

, Volume 23, Issue 7, pp 1091–1097 | Cite as

Resistance training and the risk of colon and rectal cancers

  • Terry BoyleEmail author
  • Fiona Bull
  • Lin Fritschi
  • Jane Heyworth
Original paper

Abstract

Purpose

Although there is convincing evidence that physical activity reduces colon cancer risk, research in this area has focused on aerobic activity. We conducted a case–control study to investigate whether resistance training was associated with the risk of colon and rectal cancers.

Methods

Data were collected on various colorectal cancer risk factors, including recreational physical activity performed during three age periods, from 870 cases and 996 controls in Western Australia in 2005–2007. Participants were classified as having never, possibly, or definitely performed resistance training in each age period and over the adult lifetime. The association between resistance training and colon and rectal cancer risk was analyzed using multinomial logistic regression.

Results

Participants who definitely performed resistance training in their lifetime had a non-significant reduced risk of colon cancer compared with those who did no resistance training (adjusted odds ratio (AOR) = 0.70, 95 % confidence interval (CI) = 0.45–1.11). No association was found for rectal cancer risk (AOR = 1.16, 95 % CI = 0.71–1.87). Performing resistance training was associated with a lower risk of colon cancer in each age period, although none of the relationships were statistically significant.

Conclusion

This study provides some initial evidence, albeit inconclusive, that resistance training may be inversely associated with colon cancer risk.

Keywords

Resistance training Physical activity Colon cancer Rectal cancer 

Abbreviations

AOR

Adjusted odds ratio

CI

Confidence interval

MET

Metabolic equivalent

OR

Odds ratio

Notes

Acknowledgments

The authors thank Barry Iacopetta, Kieran McCaul, David Crawford, Mehdi Tabatabaei, Cassandra Clayforth, Jenny Landrigan, Jen Girschik, Clare Tran, and Beatriz Cuesta-Briand for their contributions to the Western Australian Bowel Health Study. This work was supported by the Australian National Health and Medical Research Council (Project Grant Number 353568 and Fellowship Number 37614900 to LF), the University of Western Australia (PhD scholarship to TB), and the Lions Cancer Institute of Western Australia (PhD scholarship to TB).

References

  1. 1.
    World Cancer Research Fund, American Institute for Cancer Research (2011) WCRF/AICR systematic literature review continuous update project report: the associations between food, nutrition and physical activity and the risk of colorectal cancer. AICR, Washington, DCGoogle Scholar
  2. 2.
    Powell KE, Paluch AE, Blair SN (2011) Physical activity for health: what kind? How much? How intense? On top of what? Annu Rev Public Health 32(1):349–365PubMedCrossRefGoogle Scholar
  3. 3.
    Kruger J, Carlson S, Kohl H (2006) Trends in strength training—United States, 1998–2004. JAMA 296(12):1459–1460CrossRefGoogle Scholar
  4. 4.
    Centers for Disease Control and Prevention (2011) Data 2010: the healthy people 2010 database. Available at http://wonder.cdc.gov/data2010
  5. 5.
    Rosenberg M, Mills C, McCormack G et al (2010) Physical activity levels of Western Australian adults 2009: findings from the physical activity taskforce adult physical activity survey. Health Promotion Evaluation Unit, The University of Western Australia, Perth, AustraliaGoogle Scholar
  6. 6.
    Humphries B, Duncan MJ, Mummery WK (2010) Prevalence and correlates of resistance training in a regional Australian population. Br J Sports Med 44(9):653–656PubMedCrossRefGoogle Scholar
  7. 7.
    Winett RA, Williams DM, Davy BM (2009) Initiating and maintaining resistance training in older adults: a social cognitive theory-based approach. Br J Sports Med 43(2):114–119PubMedCrossRefGoogle Scholar
  8. 8.
    Ruiz JR, Sui X, Lobelo F et al (2009) Muscular strength and adiposity as predictors of adulthood cancer mortality in men. Cancer Epidemiol Biomarkers Prev 18(5):1468–1476PubMedCrossRefGoogle Scholar
  9. 9.
    Ciccolo JT, Carr LJ, Krupel KL, Longval JL (2010) The role of resistance training in the prevention and treatment of chronic disease. Am J Lifestyle Med 4(4):293–308CrossRefGoogle Scholar
  10. 10.
    Flack KD, Davy KP, Hulver MW et al (2011) Aging, resistance training, and diabetes prevention. J Aging Res 2011:1–12CrossRefGoogle Scholar
  11. 11.
    Hurley BF, Hanson ED, Sheaff AK (2011) Strength training as a countermeasure to aging muscle and chronic disease. Sports Med 41(4):289–306PubMedCrossRefGoogle Scholar
  12. 12.
    Phillips SM (2007) Resistance exercise: good for more than just Grandma and Grandpa’s muscles. Appl Physiol Nutr Metab 32(6):1198–1205PubMedCrossRefGoogle Scholar
  13. 13.
    Tresierras MA, Balady GJ (2009) Resistance training in the treatment of diabetes and obesity: mechanisms and outcomes. J Cardiopulm Rehabil Prev 29(2):67–75PubMedGoogle Scholar
  14. 14.
    Giovannucci E (2001) Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr 131(11):3109S–3120SPubMedGoogle Scholar
  15. 15.
    Giovannucci E (2007) Metabolic syndrome, hyperinsulinemia, and colon cancer: a review. Am J Clin Nutr 86(3):836S–842SGoogle Scholar
  16. 16.
    Canadian Society for Exercise Physiology (2011) Canadian physical activity guidelines: 2011 scientific statements. Canadian Society for Exercise Physiology, OttawaGoogle Scholar
  17. 17.
    Chief Medical Officers of England, Scotland, Wales, and Northern Ireland (2011) Start active, stay active: a report on physical activity from the four home countries’ Chief Medical Officers. Department of Health, Physical Activity, Health Improvement and Protection, LondonGoogle Scholar
  18. 18.
    World Health Organization (2010) Global recommendations on physical activity for health. World Health Organization, GenevaGoogle Scholar
  19. 19.
    Physical Activity Guidelines Advisory Committee (2008) Physical activity guidelines advisory committee report, 2008. U.S. Department of Health and Human Services, Washington, DCGoogle Scholar
  20. 20.
    Wei EK, Giovannucci E, Wu K et al (2004) Comparison of risk factors for colon and rectal cancer. Int J Cancer 108(3):433–442PubMedCrossRefGoogle Scholar
  21. 21.
    Boyle T, Heyworth J, Bull F et al (2011) Timing and intensity of recreational physical activity and the risk of subsite-specific colorectal cancer. Cancer Causes Control 22(12):1647–1658PubMedCrossRefGoogle Scholar
  22. 22.
    Chasan-Taber L, Erickson JB, McBride JW et al (2002) Reproducibility of a self-administered lifetime physical activity questionnaire among female college alumnae. Am J Epidemiol 155(3):282–291PubMedCrossRefGoogle Scholar
  23. 23.
    Friedenreich CM, Courneya KS, Bryant HE (1998) The lifetime total physical activity questionnaire: development and reliability. Med Sci Sports Exerc 30(2):266–274PubMedCrossRefGoogle Scholar
  24. 24.
    Kriska AM, Sandler RB, Cauley JA et al (1988) The assessment of historical physical activity and its relation to adult bone parameters. Am J Epidemiol 127(5):1053–1063PubMedGoogle Scholar
  25. 25.
    Potter JD, Hunter D (2008) Colorectal cancer. In: Adami H-O, Hunter D, Trichopoulos D (eds) Textbook of cancer epidemiology, 2nd edn. Oxford University Press, OxfordGoogle Scholar
  26. 26.
    Boyle T, Heyworth J, Fritschi L, Bull F (2011) Long term sedentary work and the risk of subsite-specific colorectal cancer. Am J Epidemiol 176(10):1183–1191CrossRefGoogle Scholar
  27. 27.
    Wolin KY, Yan Y, Colditz GA, Lee IM (2009) Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer 100(4):611–616PubMedCrossRefGoogle Scholar
  28. 28.
    Boyle T (2012) Physical activity and colon cancer: timing, intensity and sedentary behavior. Am J Lifestyle Med. doi: 10.1177/1559827612436932 [published online ahead of print March 5, 2012]
  29. 29.
    Pettee Gabriel KK, Morrow JR Jr, Woolsey AL (2012) Framework for physical activity as a complex and multidimensional behavior. J Phys Act Health 9(Suppl 1):S11–S18PubMedGoogle Scholar
  30. 30.
    Phillips SM, Winett RA (2010) Uncomplicated resistance training and health-related outcomes: evidence for a public health mandate. Curr Sports Med Rep 9(4):208–213PubMedGoogle Scholar
  31. 31.
    Westcott W (2009) ACSM strength training guidelines: role in body composition and health enhancement. ACSM’s Health Fit J 13(4):14–22Google Scholar
  32. 32.
    Ruiz JR, Sui X, Lobelo F et al (2008) Association between muscular strength and mortality in men: prospective cohort study. BMJ 337:88–95CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Terry Boyle
    • 1
    • 2
    Email author
  • Fiona Bull
    • 1
  • Lin Fritschi
    • 2
  • Jane Heyworth
    • 1
  1. 1.School of Population HealthThe University of Western AustraliaCrawleyAustralia
  2. 2.Western Australian Institute for Medical ResearchThe University of Western AustraliaNedlandsAustralia

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