Cancer Causes & Control

, Volume 21, Issue 12, pp 2315–2316

Association of facial skin aging and vitamin D levels in middle-aged white women

  • Anne Lynn S. Chang
  • Teresa Fu
  • Omar Amir
  • Jean Y. Tang
Letter to the Editor

DOI: 10.1007/s10552-010-9646-y

Cite this article as:
Chang, A.L.S., Fu, T., Amir, O. et al. Cancer Causes Control (2010) 21: 2315. doi:10.1007/s10552-010-9646-y

Abstract

To investigate the relationship between UV-induced skin photodamage and 25(OH) vitamin D levels, we performed a cross-sectional study in 45 female subjects aged >40. Menopausal status, smoking status, skin cancer history, oral supplement use, and season of blood draw were recorded and serum 25(OH)D measured. A single-blinded, dermatologist evaluated standardized digital facial images for overall photodamage, erythema/telangiectasias, hyperpigmentation, number of lentigines, and wrinkling. Adjusting for age and season of blood collection, women with lower photodamage scores were associated with a 5-fold increased odds of being vitamin D insufficient (OR 5.0, 95% CI: 1.1, 23). Low scores for specific photodamage parameters including erythema/telangiectasias, hyperpigmentation, and wrinkling were also significantly associated with vitamin D insufficiency. Our results suggest an association between skin aging and 25(OH)D levels.

Keywords

Vitamin D Skin aging Ultraviolet rays/adverse effects Skin/radiation effects 

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Anne Lynn S. Chang
    • 1
  • Teresa Fu
    • 1
  • Omar Amir
    • 1
  • Jean Y. Tang
    • 1
  1. 1.Department of DermatologyStanford University School of MedicineRedwood CityUSA

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