Objectively measured physical activity and sedentary time of breast cancer survivors, and associations with adiposity: findings from NHANES (2003–2006)
- 1.5k Downloads
Obesity and physical inactivity are poor prognostic indicators for breast cancer. Studies to date have relied on self-report measures of physical activity, which tend mainly to assess moderate-to-vigorous intensity leisure-time physical activity. We report the cross-sectional associations of objectively assessed physical activity and sedentary time with adiposity in a sample of breast cancer survivors from the United States.
One hundred and eleven women from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and 2005–2006 reported a history of breast cancer. Participants wore an accelerometer for 7 days, and activity levels were summarized as moderate-to-vigorous intensity (accelerometer counts/min ≥1,952), light intensity (counts/min 100–1,951), and sedentary time (counts/min <100). Anthropometric measures were taken by study staff at examination centers.
Participants spent the majority of their day in sedentary time (66%) or in light intensity activities (33%). Log moderate-to-vigorous intensity physical activity was negatively associated with adiposity (waist circumference β = −9.805 [95% CI: −15.836, −3.775]; BMI β = −3.576 [95% CI: −6.687, −0.464]). Light intensity physical activity was negatively associated with adiposity; however, the fully adjusted models did not retain statistical significance. Similarly, sedentary time was positively associated with adiposity, but the fully adjusted models were not statistically significant.
This is the first study to describe the objectively assessed physical activity and sedentary time of breast cancer survivors. Increasing moderate-to-vigorous and light intensity physical activity, and decreasing sedentary time, may assist with weight management and improve other metabolic health outcomes for breast cancer survivors.
KeywordsBreast neoplasms Adiposity Waist circumference Body mass index Health behavior
The authors thank Dr. Charles Matthews (Nutritional Epidemiology Branch, National Cancer Institute) for the provision of, and expertise relating to, the accelerometer data reduction syntax. Lynch is supported by NHMRC Program Grant funding (#301200); Dunstan is supported by a Victorian Health Promotion Foundation Public Health Research Fellowship; Healy is supported by a NHMRC (#569861)/National Heart Foundation of Australia (PH 08B 3905) Postdoctoral Fellowship; Eakin is supported by a NHMRC Senior Research Fellowship (#511001); Owen is supported by a Queensland Health Core Research Infrastructure grant and by NHMRC Program Grant funding (#301200).
- 4.Sallis J, Saelens B (2000) Assessment of physical activity by self-report: status, limitations, and future directions. Res Q Exerc Sport 71:1–14Google Scholar
- 5.International Agency for Research on Cancer (2001) Weight control and physical activity. IARC handbooks for cancer prevention. IARC Press, Lyon, p 2Google Scholar
- 10.Howard R, Freedman D, Park Y, Hollenbeck A, Schatzkin A, Leitzmann M (2008) Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP diet and health study. Cancer Cause Control 19:939–953Google Scholar
- 15.Centers for Disease Control and Prevention (CDC) National Center for Health Statistics (NCHS). NHANES 2003–2004 and 2005–2006 data files: data, docs, codebooks, SAS code. 2009: NCHSGoogle Scholar
- 16.Matthews C, Chen K, Freedson P et al (2008) Amount of time spent in sedentary behaviors in the United States, 2003–2004. Med Sci Sport Exer 167:875–881Google Scholar
- 19.Willett W, Stampfer M (1986) Total energy intake: implications for epidemiologic analyses. Am J Epidem 124:17–27Google Scholar
- 20.Agricultural Research Service, Beltsville Human Nutrition Research Center, Food Surveys Research Group, and USDA. Food and Nutrient Database for Dietary Studies, 3.0 Hyattsville, MDGoogle Scholar
- 21.Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M (2008) Physical activity in the United States measured by accelerometer. Med Sci Sport Exer 40:181–188Google Scholar