The impact of height and body mass index on the risk of testicular cancer in 600,000 Norwegian men
- 131 Downloads
The present study aimed at exploring the relations between body mass index (BMI) and stature and testicular cancer in a huge Norwegian cohort with measured height and weight. Height and weight were measured in 600,000 Norwegian men aged 14–44 years during 1963–2001. Results from parts of the study cohort have been reported previously. During follow-up, 1,357 testicular cancers were registered. Relative risks (RRs) of testicular cancer were estimated using Cox proportional hazards regression. The risk of testicular cancer decreased with adult BMI. Compared with men with normal BMI, overweight and obese men had a relative risk of cancer of 0.89 (95% CI: 0.77–1.03) and 0.83 (95% CI: 0.58–1.17). The relative risk of testicular cancer per unit increase in BMI was 0.97 (95% CI: 0.95–1.00). The risk of testicular cancer was not associated with adolescent BMI. A moderate increase in risk of seminomas was seen with increasing adult height. Compared with men with height 170–79 cm, men with height 180 cm and above had a relative risk of 1.17 (95% CI: 1.00–1.37).
KeywordsBody mass index Testicular cancer Germ cell tumors Cohort study Norway
We are grateful to those who during almost 40 years collected the data used in the present study. These are persons connected to the former National Health Screening Service, The Nord-Trøndelag Health Survey (HUNT), The Hordaland Health Survey (HUSK) and The Tromsø Study.
- 3.The Cancer Registry of Norway. The Cancer Registry of Norway. http://www.kreftregisteret.no/. March, 2006Google Scholar
- 4.IARC Working Group on the Evaluation of Cancer-Preventive Strategies (2002) Weight control and physical activity. IARC Press International Agency for Research on Cancer, LyonGoogle Scholar
- 8.Waaler HT (1984) Height, weight and mortality. The Norwegian experiment. Acta Med Scand Suppl 679:1–56Google Scholar
- 10.Bjartveit K (1997) [The National Health Screening Service: From fight against tuberculosis to many-sided epidemiological activities] Fra tuberkulosekamp til mangesidig epidemiologisk virksomhet. Nor Epidemiol 7:157–174Google Scholar
- 11.Statistics Norway. Statistics Norway. http://www.ssb.no/english/. March, 2006Google Scholar
- 12.Cox DR, Oakes D (1984) Analysis of Survival Data. Chapman and Hall Ltd., LondonGoogle Scholar
- 13.World Health Organization Consultation on Obesity. Preventing and managing the global epidemic: Report of a WHO Consultation on Obesity, Geneva, 3–5 June 1997. 1–276. 1998. Geneva, Switzerland, World Health OrganizationGoogle Scholar
- 14.Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, et al. (2000) CDC growth charts: United States. Adv Data 1–27Google Scholar
- 15.National Center for Health Statistics . CDC Growth Charts: United States. http://www.cdc.gov/growthcharts/. August, 2002Google Scholar
- 16.SPSS Inc. SPSS for Windows. Release 12.0.2. 2004Google Scholar