Cancer Causes & Control

, Volume 16, Issue 5, pp 573–578

Secular trends in the incidence, mortality, and survival rate of gastric cancer in a general Japanese population: the Hisayama study

  • Keiichi Tanaka
  • Yutaka Kiyohara
  • Michiaki Kubo
  • Takayuki Matsumoto
  • Yumihiro Tanizaki
  • Ken Okubo
  • Toshiharu Ninomiya
  • Yoshinori Oishi
  • Kentaro Shikata
  • Mitsuo Iida
Article

Abstract

To examine secular trends in the incidence and mortality of gastric cancer in a Japanese community, Hisayama, we established three study-cohorts of Hisayama residents aged ≥40 years in 1961 (1637 subjects), 1974 (2054), and 1988 (2602). Each cohort was followed up for ten years. The age-standardized mortality from gastric cancer significantly decreased from 2.4 per 1000 person-years in the first cohort to 0.8 in the third cohort for men, and from 1.0 to 0.2, respectively, for women (p < 0.01 for trend in both sexes). The five-year survival rate after gastric cancer significantly improved from the first (32.6%) to the third cohort (73.0%, p < 0.01) for men and from 43.2% to 72.3% (p < 0.05), respectively, for women. The age-standardized incidence of cancer in men was not different among the cohorts (4.3 per 1000 person-years in the first, 5.0 in the second, and 4.9 in the third cohort), while it decreased significantly in women (2.0, 1.8, and 1.2, respectively, p < 0.01 for trend). In conclusion, our findings suggest that in a Japanese population, the mortality from gastric cancer declined during the past 40 years, due mainly to the improvement of survival in both sexes and a decrease in the incidence for women.

Keywords

gastric cancer incidence mortality survival trend 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Parkin, DMWhelan, SLFerlay, JRaymond, LYoung, J eds. 1997Cancer incidence in Five ContinentsInternational Agency for Research on CancerLyonGoogle Scholar
  2. 2.
    Lambert, R, Guilloux, A, Oshima, A,  et al. 2002Incidence and mortality from stomach cancer in Japan, Slovenia and the USAInt J Cancer97811818PubMedGoogle Scholar
  3. 3.
    Tominaga, S 1987Decreasing trend of stomach cancer in JapanJpn J Cancer Res78110PubMedGoogle Scholar
  4. 4.
    Akoh, JA, Macintyre, IM 1992Improving survival in gastric cancer: review of 5-year survival rates in English language publications from 1970Br J Surg79293299PubMedGoogle Scholar
  5. 5.
    Nakamura K, Ueyama T, Yao, et al. (1992) Pathology and prognosis of gastric carcinoma. Findings in 10,000 patients who underwent primary gastrectomy. Cancer 70: 1030–1037Google Scholar
  6. 6.
    Hisamichi, S 1989Screening for gastric cancerWorld J Surg133137PubMedGoogle Scholar
  7. 7.
    The Research Group for Population-based Cancer Registration in Japan (1998) Cancer incidence in Japan, 1985–89: re-estimation based on data from eight population-based cancer registries. Jpn J Clin Oncol 28: 54–67Google Scholar
  8. 8.
    Hanai, A, Kitagawa, T, Ajika, W, Tsukuma, H, Oshima, A 1998Cancer incidence in Japan in 1990:estimates based on data from Population-based Cancer Registries. The Research Group for Population-based Cancer Registration in JapanJpn J Clin Oncol28450453PubMedGoogle Scholar
  9. 9.
    Schrijvers, CT, Stronks, K, Mheen, DH, Coebergh, JW, Mackenbach, JP 1994Validation of cancer prevalence data from a postal survey by comparison with cancer registry recordsAm J Epidemiol139408414PubMedGoogle Scholar
  10. 10.
    Katsuki, S 1966Epidemiological and clinicopathological study on cerebrovascular disease in JapanProg Brain Res216489PubMedGoogle Scholar
  11. 11.
    Ohmura, T, Ueda, K, Kiyohara, Y,  et al. 1993Prevalence of type 2 (non-insulin-dependent) diabetes mellitus and impaired glucose tolerance in the Japanese general population: the Hisayama StudyDiabetologia3611981203CrossRefPubMedGoogle Scholar
  12. 12.
    Yamagata, H, Kiyohara, Y, Aoyagi, K,  et al. 2000Impact of Helicobacter pylori infection on gastric cancer incidence in a general Japanese population: the Hisayama studyArch Intern Med16019621968CrossRefPubMedGoogle Scholar
  13. 13.
    Ueda, K, Omae, T, Hirota, Y,  et al. 1981Decreasing trend in incidence and mortality from stroke in Hisayama residents, JapanStroke12154160PubMedGoogle Scholar
  14. 14.
    Fujishima, M, Kiyohara, Y, Kato, I,  et al. 1996Diabetes and cardiovascular disease in a prospective population survey in Japan: the Hisayama StudyDiabetes45S14S16Google Scholar
  15. 15.
    Cox, DR 1972Regression models and life-tablesJ R Stat Soc34187220Google Scholar
  16. 16.
    Kamineni, A, Williams, MA, Schwartz, SM, Cook, LS, Weiss, NS 1999The incidence of gastric carcinoma in Asian migrants to the United States and their descendantsCancer Causes Control107783CrossRefPubMedGoogle Scholar
  17. 17.
    Cavelaars, AE, Kunst, AE, Geurts, JJ,  et al. 2000Educational differences in smoking: international comparisonBMJ32011021107CrossRefPubMedGoogle Scholar
  18. 18.
    Shirota, T, Magome, A, Miyamoto, N,  et al. 1999Changes of nutrient intakes and food consumption structure over a 30-years period in HisayamaBulletin of Nakamura Gakuen College & Nakamura Gakuen Junior College31141151Google Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • Keiichi Tanaka
    • 1
  • Yutaka Kiyohara
    • 1
  • Michiaki Kubo
    • 1
  • Takayuki Matsumoto
    • 1
  • Yumihiro Tanizaki
    • 1
  • Ken Okubo
    • 1
  • Toshiharu Ninomiya
    • 1
  • Yoshinori Oishi
    • 1
  • Kentaro Shikata
    • 1
  • Mitsuo Iida
    • 1
  1. 1.Department of Medicine and Clinical Science, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  2. 2.Department of Medicine and Clinical Science, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

Personalised recommendations