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Breast Cancer Research and Treatment

, Volume 171, Issue 3, pp 685–692 | Cite as

Extremely brief mindfulness interventions for women undergoing breast biopsies: a randomized controlled trial

  • Bertha Andrade Coelho
  • Sara de Pinho Cunha Paiva
  • Agnaldo Lopes da Silva Filho
Clinical trial

Abstract

Purpose

Mindfulness-based programs can reduce stress and help practitioners to have positive attitudes in their daily lives. This randomized controlled trial evaluated the impact of brief Mindfulness interventions on quantitative and qualitative stress parameters in patients undergoing imaging-guided breast biopsies.

Methods

Eighty-two women undergoing percutaneous imaging-guided breast biopsy were randomized into two groups: MBI group or standard care group. One week before the biopsy procedure, on the waiting room and during the biopsy procedure, the MBI group was exposed to mindfulness techniques and the standard care group received supportive dialogue from the biopsy team. Participants completed questionnaires measuring depression, anxiety and stress, demographics, and medical history, besides evaluating their pain experience through a visual analogue scale for pain and had their systolic and diastolic blood pressure, initial and final temperate, heart rate, oxygen saturation, and salivary cortisol measured.

Results

Participation in the mindfulness intervention group was associated with reduced levels of perceived stress, blood pressure, heart rate, and oxygen saturation compared to participation in the standard care group (P values < 0.05). No difference was observed regarding salivary cortisol levels, peripheral temperature, and pain perception between the two studied groups.

Conclusion

Results indicate that an extremely brief mindfulness intervention is a feasible intervention, suggesting that Mindfulness-based programs may be beneficial to reduce discomfort in acutely stressful settings.

Keywords

Mindfulness Breast biopsy Stress markers Salivary cortisol 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all participants included in the study.

References

  1. 1.
    Haller H, Winkler MM, Klose P, Dobos G, Kümmel S, Cramer H (2017) Mindfulness-based interventions for women with breast cancer: an updated systematic review and meta-analysis. Acta Oncologica 56:1–12CrossRefGoogle Scholar
  2. 2.
    Sickles EA, D’Orsi CJ (2013) ACR BI-RADS® Follow-up and outcome monitoring. In: ACR BI-RADS® Atlas, Breast Imaging Reporting and Data System, 5th edn. American College of Radiology, RestonGoogle Scholar
  3. 3.
    Hayes Balmadrid MA, Shelby RA, Wren AA, Miller LS, Yoon SC, Baker JA et al (2017) Anxiety prior to breast biopsy: relationships with length of time from breast biopsy recommendation to biopsy procedure and psychosocial factors. J Health Psychol 22(5):561–571CrossRefPubMedGoogle Scholar
  4. 4.
    Soo MS, Jarosz JA, Wren AA, Soo AE, Mowery YM, Johnson KS et al (2016) Imaging-guided core-needle breast biopsy: impact of meditation and music interventions on patient anxiety, pain, and fatigue. J Am Coll Radiol 13(5):526–534CrossRefPubMedGoogle Scholar
  5. 5.
    Carlson LE, Garland SN (2005) Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. Int J Behav Med 12(4):278–285CrossRefPubMedGoogle Scholar
  6. 6.
    Rosenzweig S, Greeson JM, Reibel DK, Green JS, Jasser SA, Beasley D (2010) Mindfulness-based stress reduction for chronic pain conditions: variation in treatment outcomes and role of home meditation practice. J Psychosom Res 68(1):29–36CrossRefPubMedGoogle Scholar
  7. 7.
    Tang YY, Hölzel BK, Posner MI (2015) The neuroscience of mindfulness meditation. Nat Rev Neurosci 16(4):213–225CrossRefPubMedGoogle Scholar
  8. 8.
    Marchand WR (2014) Neural mechanisms of mindfulness and meditation: evidence from neuroimaging studies. World J Radiol 6(7):471–479CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Witek-Janusek L, Albuquerque K, Chroniak KR, Chroniak C, Durazo-Arvizu R, Mathews HL (2008) Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun 22(6):969–981CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    O’Leary K, O’Neill S, Dockray S (2016) A systematic review of the effects of mindfulness interventions on cortisol. J Health Psychol 21(9):2108–2121CrossRefPubMedGoogle Scholar
  11. 11.
    Gilmartin H, Goyal A, Hamati MC, Mann J, Saint S, Chopra V (2017) Brief mindfulness practices for healthcare providers—a systematic literature review. Am J Med 130(10):1219–1217CrossRefPubMedGoogle Scholar
  12. 12.
    Matousek RH, Pruessner JC, Dobkin PL (2011) Changes in the cortisol awakening response (CAR) following participation in mindfulness-based stress reduction in women who completed treatment for breast cancer. Complement Ther Clin Pract 17(2):65–70CrossRefPubMedGoogle Scholar
  13. 13.
    Gotink RA, Chu P, Busschbach JJ, Benson H, Fricchione GL, Hunink MM (2015) Standardized mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs. PloS ONE 10(4):1–17CrossRefGoogle Scholar
  14. 14.
    Ussher M, Spatz A, Copland C, Nicolaou A, Cargill A, Amini-Tabrizi N et al (2014) Immediate effects of a brief mindfulness-based body scan on patients with chronic pain. J Behav Med 37(1):127–134CrossRefPubMedGoogle Scholar
  15. 15.
    Cramer H, Lauche R, Paul A, Dobos G (2012) Mindfulness-based stress reduction for breast cancer—a systematic review and meta-analysis. Curr Oncol 19(5):343–352CrossRefGoogle Scholar
  16. 16.
    Nakamura Y, Lipschitz DL, Kuhn R, Kinney AY, Donaldson GW (2013) Investigating efficacy of two brief mind–body intervention programs for managing sleep disturbance in cancer survivors: a pilot randomized controlled trial. J Cancer Surviv 7(2):165–182CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    Ferreira APM, Paiva SPC, Lima SSS, Felicíssimo MF, Nogueira-Rodrigues A, Carneiro MM et al (2017) The Impact of Mindfulness-based Interventions on the Wellbeing of cervical cancer patients on chemoradiotherapy. Obstet Gynecol Int J 6(6):00091Google Scholar
  18. 18.
    Bugbee ME, Wellisch DK, Arnott IM, Maxwell JR, Kirsch DL, Sayre JW et al (2005) Breast core-needle biopsy: clinical trial of relaxation technique versus medication versus no intervention for anxiety reduction. Radiology 234(1):73–78CrossRefPubMedGoogle Scholar
  19. 19.
    Zainal NZ, Booth S, Huppert FA (2013) The efficacy of mindfulness-based stress reduction on mental health of breast cancer patients: a meta-analysis. Psycho-Oncology 22(7):1457–1465CrossRefPubMedGoogle Scholar
  20. 20.
    Gold E, Smith A, Hopper I, Herne D, Tansey G, Hulland C (2010) Mindfulness-based stress reduction (MBSR) for primary school teachers. J Child Fam Stud 19(2):184–189CrossRefGoogle Scholar
  21. 21.
    Srinivasan J, Breheny PJ (2012) Meditation for quality improvement of medical encounters: single-intervention, vedanta-based meditation effects on vital signs and mood indices. J Evid Based Complement Alt Med 17(2):96–103CrossRefGoogle Scholar
  22. 22.
    Khoury B, Sharma M, Rush SE, Fournier C (2015) Mindfulness-based stress reduction for healthy individuals: a meta-analysis. J Psychosom Res 78(6):519–528CrossRefPubMedGoogle Scholar
  23. 23.
    Song Y, Lindquist R (2015) Effects of mindfulness-based stress reduction on depression, anxiety, stress and mindfulness in Korean nursing students. Nurse Educ Today 35(1):86–90CrossRefPubMedGoogle Scholar
  24. 24.
    Chaya MS, Kurpad AV, Nagendra HR, Nagarathna R (2006) The effect of long term combined yoga practice on the basal metabolic rate of healthy adults. BMC Complement Alt Med 6(1):1–6CrossRefGoogle Scholar
  25. 25.
    Sanada K, Montero-Marin J, Díez MA, Salas-Valero M, Pérez-Yus MC, Morillo H et al (2016) Effects of Mindfulness-based interventions on salivary cortisol in healthy adults: a meta-analytical review. Front Physiol 7:1–12CrossRefGoogle Scholar
  26. 26.
    Hawker GA, Mian S, Kendzerska T, French M (2011) Measures of adult pain: visual analog scale for pain (VAS Pain), numeric rating scale for pain (NRS Pain), Mcgill pain questionnaire (MPQ), short-form mcgill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care Res 63(S11):S240–S252CrossRefGoogle Scholar
  27. 27.
    Bird ML, Callisaya ML, Cannell J, Gibbons T, Smith ST, Ahuja KD (2016 Jan) Accuracy, validity, and reliability of an electronic visual analog scale for pain on a touch screen tablet in healthy older adults: a clinical trial. Interact J Med Res 5(1):1–8CrossRefGoogle Scholar
  28. 28.
    Garland EL, Baker AK, Larsen P, Riquino MR, Priddy SE, Thomas E et al (2017) Randomized controlled trial of brief mindfulness training and hypnotic suggestion for acute pain relief in the hospital setting. J Gen Intern Med 32(10):1106–1113CrossRefPubMedGoogle Scholar
  29. 29.
    Pang E, Crystal P, Kulkarni S, Murphy K, Menezes RJ (2016) An audit of pain experienced during image-guided breast biopsy procedures at an academic center. Can Assoc Radiol J 67(3):250–253CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Bertha Andrade Coelho
    • 1
    • 2
  • Sara de Pinho Cunha Paiva
    • 3
  • Agnaldo Lopes da Silva Filho
    • 1
    • 3
  1. 1.Department of Gynecology and Obstetrics of the School of Medicine of UNESP – Universidade Estadual Paulista “Júlio de Mesquita Filho”BotucatuBrazil
  2. 2.Faculty of MedicineFIP-MOC, Faculdades Integradas Pitágoras de Montes ClarosMontes ClarosBrazil
  3. 3.Department of Gynecology and Obstetrics, Faculty of MedicineUFMG, Federal University of Minas GeraisBelo HorizonteBrazil

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