Breast Cancer Research and Treatment

, Volume 171, Issue 3, pp 685–692 | Cite as

Extremely brief mindfulness interventions for women undergoing breast biopsies: a randomized controlled trial

  • Bertha Andrade CoelhoEmail author
  • Sara de Pinho Cunha Paiva
  • Agnaldo Lopes da Silva Filho
Clinical trial



Mindfulness-based programs can reduce stress and help practitioners to have positive attitudes in their daily lives. This randomized controlled trial evaluated the impact of brief Mindfulness interventions on quantitative and qualitative stress parameters in patients undergoing imaging-guided breast biopsies.


Eighty-two women undergoing percutaneous imaging-guided breast biopsy were randomized into two groups: MBI group or standard care group. One week before the biopsy procedure, on the waiting room and during the biopsy procedure, the MBI group was exposed to mindfulness techniques and the standard care group received supportive dialogue from the biopsy team. Participants completed questionnaires measuring depression, anxiety and stress, demographics, and medical history, besides evaluating their pain experience through a visual analogue scale for pain and had their systolic and diastolic blood pressure, initial and final temperate, heart rate, oxygen saturation, and salivary cortisol measured.


Participation in the mindfulness intervention group was associated with reduced levels of perceived stress, blood pressure, heart rate, and oxygen saturation compared to participation in the standard care group (P values < 0.05). No difference was observed regarding salivary cortisol levels, peripheral temperature, and pain perception between the two studied groups.


Results indicate that an extremely brief mindfulness intervention is a feasible intervention, suggesting that Mindfulness-based programs may be beneficial to reduce discomfort in acutely stressful settings.


Mindfulness Breast biopsy Stress markers Salivary cortisol 


Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Bertha Andrade Coelho
    • 1
    • 2
    Email author
  • Sara de Pinho Cunha Paiva
    • 3
  • Agnaldo Lopes da Silva Filho
    • 1
    • 3
  1. 1.Department of Gynecology and Obstetrics of the School of Medicine of UNESP – Universidade Estadual Paulista “Júlio de Mesquita Filho”BotucatuBrazil
  2. 2.Faculty of MedicineFIP-MOC, Faculdades Integradas Pitágoras de Montes ClarosMontes ClarosBrazil
  3. 3.Department of Gynecology and Obstetrics, Faculty of MedicineUFMG, Federal University of Minas GeraisBelo HorizonteBrazil

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