Breast Cancer Research and Treatment

, Volume 161, Issue 3, pp 443–452 | Cite as

Effects of exercise intervention in breast cancer patients: is mobile health (mHealth) with pedometer more effective than conventional program using brochure?

  • Kyeong Eun Uhm
  • Ji Sung Yoo
  • Seung Hyun Chung
  • Jong Doo Lee
  • Ilkyun Lee
  • Joong Il Kim
  • Se Kyung Lee
  • Seok Jin Nam
  • Yong Hyun Park
  • Ji Youl LeeEmail author
  • Ji Hye HwangEmail author
Clinical trial



To investigate and compare the effects of mobile health (mHealth) and pedometer with conventional exercise program using a brochure on physical function and quality of life (QOL).


The study was a prospective, quasi-randomized multicenter trial where 356 patients whose cancer treatment had been terminated were enrolled. All patients were instructed to perform a 12-week regimen of aerobic and resistance exercise. The mHealth group received a pedometer and a newly developed smartphone application to provide information and monitor the prescribed exercises. Those in the conventional group received an exercise brochure. Physical measurements were conducted at baseline, 6 weeks, and 12 weeks. Self-reported physical activity (international physical activity questionnaire-short form), general QOL (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30), and breast cancer-specific QOL (Quality of Life Questionnaire Breast Cancer Module 23) were assessed at baseline and 12 weeks. A user satisfaction survey was assessed in the mHealth group.


Basic characteristics were not different between the two groups except for age and previous radiotherapy. Physical function, physical activity, and QOL scores were significantly improved regardless of the intervention method, and changes were not significantly different between the two groups. Additionally, the mean Likert scale response for overall satisfaction with the service was 4.27/5 in the mHealth group.


Overall, both the mHealth coupled with pedometer and conventional exercise education using a brochure were effective in improving physical function, physical activity, and QOL. This study provides a basis of mHealth research in breast cancer patients for progressing further developing field, although superiority of the mHealth over the conventional program was not definitely evident.


Mobile health Pedometer Telemedicine Exercise Breast cancer 



This research was supported by the National Information Society Agency (NIA) funded by the Ministry of Science, ICT and Future Planning (Smart After Care Service for Cancer and Cardiac Disease).

Compliance with ethical standards

Conflict of interests

The authors declare that they have no conflicts of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Supplementary material

10549_2016_4065_MOESM1_ESM.tif (280 kb)
Supplementary material 1 (TIFF 279 kb)
10549_2016_4065_MOESM2_ESM.tif (699 kb)
Supplementary material 2 (TIFF 699 kb)


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Kyeong Eun Uhm
    • 1
    • 2
  • Ji Sung Yoo
    • 3
  • Seung Hyun Chung
    • 3
  • Jong Doo Lee
    • 4
  • Ilkyun Lee
    • 4
    • 5
  • Joong Il Kim
    • 4
  • Se Kyung Lee
    • 6
  • Seok Jin Nam
    • 6
  • Yong Hyun Park
    • 7
  • Ji Youl Lee
    • 7
    Email author
  • Ji Hye Hwang
    • 1
    Email author
  1. 1.Department of Physical and Rehabilitation Medicine, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulKorea
  2. 2.Department of Rehabilitation MedicineKonkuk University School of MedicineSeoulKorea
  3. 3.Department of Rehabilitation MedicineNational Cancer CenterGyeonggi-doKorea
  4. 4.Institute for Integrative Medicine, International St. Mary’s HospitalCatholic Kwandong UniversityIncheonKorea
  5. 5.Department of Surgery, International St. Mary’s HospitalCatholic Kwandong UniversityIncheonKorea
  6. 6.Department of Surgery, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulKorea
  7. 7.Department of Urology, Seoul St. Mary’s HospitalThe Catholic University of Korea College of MedicineSeoulKorea

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