To be young, Black, and living with breast cancer: a systematic review of health-related quality of life in young Black breast cancer survivors
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Compared with young White women, young Black women are more likely to present with aggressive breast cancer (BC) subtypes that are potentially linked to worse health-related quality of life (HRQOL); however, there is limited consensus regarding HRQOL needs among young Black BC survivors. Employing Ferrell’s framework on QOL in BC (i.e., physical, psychological, social, and spiritual well-being), we conducted a systematic review on HRQOL among Black BC survivors aged <50 years and proposed recommendations for advancing HRQOL research and care for this population.
Literature searches were conducted in MEDLINE/PubMed, EMBASE, CINAHL, and PsycINFO to identify relevant articles published from 1995 to 2015. Abstracts and full-text articles were screened using predetermined inclusion/exclusion criteria and evaluated for quality.
A total of 2533 articles were identified, but six met eligibility criteria. Most studies examined multiple HRQOL domains, with the psychological domain most represented. Compared with their older, White, and BC-free counterparts, young Black BC survivors reported greater fear of dying, unmet supportive care needs, financial distress, and lower physical/functional well-being. However, spiritual well-being appeared favorable for young Black survivors. Research gaps include the absence of longitudinal studies and under-representation of studies examining physical, social, and particularly, spiritual HRQOL in young Black BC survivors.
Young Black BC survivors generally experience suboptimal HRQOL after BC diagnosis. As few studies have reported on HRQOL among this group, future research and oncology care should prioritize young Black women in ways that recognize their unique concerns, in order to ensure better HRQOL outcomes both during and after treatment.
KeywordsBreast cancer Black African-American Premenopausal Quality of life
CAS and SBW have received a Research Grant from Pfizer for another unrelated study. This article is dedicated in memory of Meleshia Daye, whose courage and strength as a Young Black Woman with Breast Cancer inspired this contribution to research and clinical practice.
Compliance with ethical standards
Conflict of Interest
All other authors have no conflicts of interest to disclose.
- 1.WHO (2013) Breast cancer: prevention and control. World Health Organization. http://www.who.int/cancer/detection/breastcancer/en/index1.html. Accessed 24 Sept 2013
- 2.ACS (2015) Breast cancer facts and figures 2015–2016. Am Cancer Soc. Access 02(03/2016):2016Google Scholar
- 3.Harper S, Lynch J, Meersman SC, Breen N, Davis WW, Reichman MC (2009) Trends in area-socioeconomic and race-ethnic disparities in breast cancer incidence, stage at diagnosis, screening, mortality, and survival among women ages 50 years and over (1987–2005). Cancer Epidemiol Biomarkers Prev 18(1):121–131. doi: 10.1158/1055-9965.epi-08-0679 CrossRefPubMedGoogle Scholar
- 5.Chlebowski RT, Chen Z, Anderson GL, Rohan T, Aragaki A, Lane D, Dolan NC, Paskett ED, McTiernan A, Hubbell FA, Adams-Campbell LL, Prentice R (2005) Ethnicity and breast cancer: factors influencing differences in incidence and outcome. J Natl Cancer Inst 97(6):439–448. doi: 10.1093/jnci/dji064 CrossRefPubMedGoogle Scholar
- 6.Newman LA, Mason J, Cote D, Vin Y, Carolin K, Bouwman D, Colditz GA (2002) African–American ethnicity, socioeconomic status, and breast cancer survival: a meta-analysis of 14 studies involving over 10,000 African–American and 40,000 White American patients with carcinoma of the breast. Cancer 94(11):2844–2854. doi: 10.1002/cncr.10575 CrossRefPubMedGoogle Scholar
- 11.Millikan RC, Newman B, Tse CK, Moorman PG, Conway K, Dressler LG, Smith LV, Labbok MH, Geradts J, Bensen JT, Jackson S, Nyante S, Livasy C, Carey L, Earp HS, Perou CM (2008) Epidemiology of basal-like breast cancer. Breast Cancer Res Treat 109(1):123–139. doi: 10.1007/s10549-007-9632-6 CrossRefPubMedGoogle Scholar
- 13.Ahles TA, Saykin AJ, Furstenberg CT, Cole B, Mott LA, Titus-Ernstoff L, Skalla K, Bakitas M, Silberfarb PM (2005) Quality of life of long-term survivors of breast cancer and lymphoma treated with standard-dose chemotherapy or local therapy. J Clin Oncol 23(19):4399–4405. doi: 10.1200/jco.2005.03.343 CrossRefPubMedPubMedCentralGoogle Scholar
- 17.Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V (2007) Descriptive analysis of estrogen receptor (ER)−negative, progesterone receptor (PR)−negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer registry. Cancer 109(9):1721–1728. doi: 10.1002/cncr.22618 CrossRefPubMedGoogle Scholar
- 20.Smith AW, Alfano CM, Reeve BB, Irwin ML, Bernstein L, Baumgartner K, Bowen D, McTiernan A, Ballard-Barbash R (2009) Race/ethnicity, physical activity, and quality of life in breast cancer survivors. Cancer Epidemiol Biomark Prev 18(2):656–663. doi: 10.1158/1055-9965.epi-08-0352 CrossRefGoogle Scholar
- 26.Von Ah DM, Russell KM, Carpenter J, Monahan PO, Qianqian Z, Tallman E, Ziner KW, Storniolo AM, Miller KD, Giesler RB, Haase J, Otte J, Champion VL (2012) Health-related quality of life of african american breast cancer survivors compared with healthy African American women. Cancer Nurs 35(5):337–346. doi: 10.1097/NCC.0b013e3182393de3 CrossRefGoogle Scholar
- 31.Mor V, Malin M, Allen S (1994) Age differences in the psychosocial problems encountered by breast cancer patients. J Natil Cancer Inst Monogr 16:191–197Google Scholar
- 44.Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (2016) SEER Cancer Statistics Review, 1975–2013. National Cancer Institute, BethesdaGoogle Scholar
- 45.ACS (2014) Life after cancer: survivorship by the numbers. American Cancer SocietyGoogle Scholar
- 47.CASP (2014) Critical appraisal skills programme (CASP). CASP ChecklistsGoogle Scholar
- 59.Morrow PK, Broxson AC, Munsell MF, Basen-Enquist K, Rosenblum CK, Schover LR, Nguyen LH, Hsu L, Castillo L, Hahn KM, Litton JK, Kwiatkowski DN, Hortobagyi GN (2014) Effect of age and race on quality of life in young breast cancer survivors. Clin Breast Cancer 14(2):e21–e31. doi: 10.1016/j.clbc.2013.10.003 CrossRefPubMedGoogle Scholar
- 67.MCC (2013) Psychological distress screening in cancer patients. Michigan Cancer Consortium, LansingGoogle Scholar
- 68.CoC (2012) Cancer program standards 2012: ensuring patient-centered care. American College of Surgeons, ChicagoGoogle Scholar
- 69.NCCN (2016) NCCN Distress thermometer and problem list for patients, 1st edn. National Comprehensive Cancer Network, WashingtonGoogle Scholar
- 70.Dabrowski M, Boucher K, Ward JH, Lovell MM, Sandre A, Bloch J, Carlquist L, Porter M, Norman L, Buys SS (2007) Clinical experience with the NCCN distress thermometer in breast cancer patients. J Natl Compr Cancer Netw 5(1):104–111Google Scholar
- 72.Woods-Giscombé CL, Black AR (2010) Mind-Body interventions to reduce risk for health disparities related to stress and strength among African American women: the potential of mindfulness-based stress reduction, loving-kindness, and the NTU therapeutic framework. Complement Health Pract Rev 15(3):115–131. doi: 10.1177/1533210110386776 PubMedPubMedCentralGoogle Scholar
- 73.Duckett PAS (2013) Health coverage for the black population today and under the affordable care Ac. The Henry J Kaiser Family Foundation, Menlo ParkGoogle Scholar