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Breast Cancer Research and Treatment

, Volume 158, Issue 3, pp 509–522 | Cite as

Effect of a multidiscipline mentor-based program, Be Resilient to Breast Cancer (BRBC), on female breast cancer survivors in mainland China—A randomized, controlled, theoretically-derived intervention trial

  • Zeng Jie Ye
  • Mu Zi Liang
  • Hong Zhong Qiu
  • Mei Ling Liu
  • Guang Yun Hu
  • Yun Fei Zhu
  • Zhen Zeng
  • Jing Jing Zhao
  • Xiao Ming Quan
Clinical trial

Abstract

To reduce the risk of adjustment problems for breast cancer patients in mainland China, we examined the efficacy of a multidiscipline mentor-based program, Be Resilient to Breast Cancer (BRBC), delivered after breast surgery to (a) increase protective factors of social support, hope for the future, etc.; (b) decrease risk factors of Physical and Emotional Distress; and (c) increase outcomes of Resilience, Transcendence and Quality of Life (QOL). A multisite randomized controlled trial was conducted at 6 specialist cancer hospitals. 101 and 103 breast cancer patients were allocated to intervention group (IG) and control group (CG), respectively, and 112 general females (without breast cancer) were allocated to the norm group (NG). Participants completed measures that were related to latent variables derived from the Resilience Model for Breast Cancer (RM-BC) at baseline (T1), 2 months (T2), 6 months (T3), and 12 months (T4) after intervention. At T2, the IG reported significantly lower Depression (ES = 0.65,P = 0.0019) and Illness Uncertainty (ES = 0.57, P = 0.004), better Hope (ES = 0.81, P < 0.001) and QOL (ES = 0.60, P = 0.002) than did the CG. At T3, the IG reported significantly lower Anxiety (ES = 0.74, P < 0.001), better Social Support (ES = 0.51,P = 0.009), Transcendence (ES = 0.87, P < 0.001), and Resilience (ES = 0.83, P < 0.001) compared with the CG. At T4, the IG reported better Resilience though not significant (P = 0.085) and better Transcendence (P = 0.0243) than did the NG. The BRBC intervention improves the positive health outcomes and decreases the risk factors of illness-related distress of breast cancer patients during the high-risk cancer treatment.

Keywords

Resilience Breast cancer Survivors Mentor-based Multidiscipline Theoretically-derived Randomized trial Mainland China 

Notes

Acknowledgments

The authors gratefully acknowledge the assistance of the patients with breast cancer who participated in this study. The contribution made by the hospitals and the university is also acknowledged.

Author contributions

The following authors or their immediate family members have indicated no financial interest. No conflict exists for drugs or devices used in a study if they are not being evaluated as part of the investigation. Research Funding: Zeng Jie Ye; Xiao Ming Quan Conception and design: Zeng Jie Ye; Mu Zi Liang; Hong Zhong Qiu; Xiao Ming Quan. Administrative support: Zeng Jie Ye; Xiao Ming Quan Provision of study materials or patients: Mu Zi Liang; Hong Zhong Qiu; Mei Ling Liu; Guang Yun Hu; Zeng Zeng; Yun Fei Zhu; Jing Jing Zhao. Collection and assembly of data: Mu Zi Liang; Hong Zhong Qiu; Mei Ling Liu; Guang Yun Hu; Zeng Zeng; Yun Fei Zhu; Jing Jing Zhao. Data analysis and interpretation: Zeng Jie Ye; Mu Zi Liang; Hong Zhong Qiu; Xiao Ming Quan. Manuscript writing: All authors Final approval of manuscript: All authors.

Compliance with Ethical Standards

Conflict of interest

The authors have no financial disclosures or conflicts of interest to make.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.College of Economics and ManagementGuangzhou University of Chinese MedicineGuangzhouChina
  2. 2.The First Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhouChina
  3. 3.Guangzhou University of Chinese MedicineGuangzhouChina
  4. 4.Sun Yat-sen University Cancer CenterGuangzhouChina
  5. 5.The Second Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhouChina
  6. 6.Nursing Department of The First Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhouChina

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