The simplified Chinese version of the FACT-B was evaluated by QOL data measured from 376 patients with breast cancer. The results showed that test–retest reliability for five domains: physical well-being, social/family well-being, emotional well-being, functional well-being, additional concerns, and the overall scales and trial outcome index were 0.82, 0.85, 0.91, 0.86, 0.90, 0.84 and 0.91, 0.89 respectively. The internal consistency α for the five domains mentioned above were 0.85, 0.82, 0.84, 0.84 and 0.59 respectively. Correlation analysis, factor analysis and structural equation model showed good construct validity. Criterion-related validity was also confirmed using QLICP-BR as a criterion. The instrument can find the change of QOL for cancer patients after treatment. It’s concluded that the simplified Chinese version of FACT-B can be used to measure QOL for Chinese patients with breast cancer with good validity, reliability and responsiveness.
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In carrying out this research project, we really appreciate the help from the staff at the Oncological Hospital of Yunnan Province. The help from David Cella, Sonya Eremenco, Benjamin J. Arnold and Hiramatsu Toshiko of the Center on Outcomes, Research, and Education (CORE), Evanston- Northwestern Healthcare is also acknowledged.
This research is sponsored by the Natural Sciences Funds of Yunnan Province (99C0016G).
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Wan, C., Zhang, D., Yang, Z. et al. Validation of the simplified Chinese version of the FACT-B for measuring quality of life for patients with breast cancer. Breast Cancer Res Treat 106, 413 (2007). https://doi.org/10.1007/s10549-007-9511-1
- Breast cancer
- Quality of life
- Structural equation model